Photoredox Catalysis Unlocks Single-Electron Elementary Steps in Transition Metal Catalyzed Cross-Coupling.
Photoredox Catalysis Unlocks Single-Electron Elementary Steps in Transition Metal Catalyzed Cross-Coupling.
复制标题
DOI：
10.1021/acscentsci.6b00090
复制
发表时间：
2016-05-25
影响因子：
18.2
通讯作者：
Toste FD
中科院分区：
文献类型：
--
作者：
Levin MD;Kim S;Toste FD
自最初的报道以来，采用光氧化还原催化剂来获得新的反应性的交叉偶联技术已经以越来越快的速度发展。在本展望中，最近文献中的突出例子是基于光氧化还原催化实现的元素转化进行组织的，并在化学计量有机金属化学的相关历史先例的背景下进行讨论。这种处理允许奇电子过渡金属反应性所固有的机制相似性被推广到一组未来反应发展的经验教训。综述了光氧化还原催化对过渡金属催化交叉偶联反应的影响，并从机理的角度讨论了每个基本步骤的单电子类似物。
Since initial reports, cross-coupling technologies employing photoredox catalysts to access novel reactivity have developed with increasing pace. In this Outlook, prominent examples from the recent literature are organized on the basis of the elementary transformation enabled by photoredox catalysis and are discussed in the context of relevant historical precedent in stoichiometric organometallic chemistry. This treatment allows mechanistic similarities inherent to odd-electron transition metal reactivity to be generalized to a set of lessons for future reaction development. The influence of photoredox catalysis on transition metal catalyzed cross-coupling is reviewed, with single-electron analogues of each elementary step discussed from a mechanistic perspective.