Human African trypanosomiasis control: Achievements and challenges.

Human African trypanosomiasis control: Achievements and challenges.
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DOI:
10.1371/journal.pntd.0005454
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发表时间:
2017-04
影响因子:
3.8
通讯作者:
Van Den Abbeele J
Van Den Abbeele J
中科院分区:
医学2区
文献类型:
--
作者:
Aksoy S;Buscher P;Lehane M;Solano P;Van Den Abbeele J

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昏睡病,也称为人类非洲锥虫病 (HAT),是一种被忽视的疾病,影响着生活在撒哈拉以南非洲 155 万平方公里土地上的 7000 万人。自 20 世纪初以来,撒哈拉以南非洲地区发生了多次 HAT 流行病,最近一次流行于 20 世纪 90 年代,导致 1990 年至 2015 年间报告了约 50 万例 HAT 病例。在此,我们回顾了当前 HAT 疾病的状况以及可用于控制的工具箱。我们还强调了未来正在开发的新的或改进的干预措施的机会。
Sleeping sickness, also known as human African trypanosomiasis (HAT), is a neglected disease that impacts 70 million people living in 1.55 million km2 in sub-Saharan Africa. Since the beginning of the 20th century, there have been multiple HAT epidemics in sub-Saharan Africa, with the most recent epidemic in the 1990s resulting in about half a million HAT cases reported between 1990 and 2015. Here we review the status of HAT disease at the current time and the toolbox available for its control. We also highlight future opportunities under development towards novel or improved interventions.