Cu(OTf)2:: a reusable catalyst for high-yield synthesis of 3,4-dihydropyrimidin-2(1H)-ones

Cu(OTf)2:: a reusable catalyst for high-yield synthesis of 3,4-dihydropyrimidin-2(1H)-ones
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DOI:
10.1016/s0040-4039(03)00619-1
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发表时间:
2003-04-14
影响因子:
1.8
通讯作者:
Sudalai, A
Sudalai, A
中科院分区:
化学4区
文献类型:
--
作者:
Paraskar, AS;Dewkar, GK;Sudalai, A

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三氟甲磺酸铜(II)可有效催化乙腈中醛、β-酮酯和脲的三组分缩合反应,以高产率生成相应的3,4-二氢嘧啶-2(1H)-酮。该催化剂表现出显着的可重复使用活性。 (C) 2003 Elsevier Science Ltd. 保留所有权利。
Copper(II) triflate catalyzes efficiently the three-component condensation reaction of an aldehyde, beta-ketoester and urea in acetonitrile to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones in high yields. The catalyst exhibited remarkable reusable activity. (C) 2003 Elsevier Science Ltd. All rights reserved.