The feasibility of using microwave-induced thermoacoustic tomography for detection and evaluation of renal calculi
The feasibility of using microwave-induced thermoacoustic tomography for detection and evaluation of renal calculi
复制标题
微波热声断层扫描检测和评估肾结石的可行性
DOI：
10.1088/0031-9155/55/17/020
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发表时间：
2010-09-07
影响因子：
3.5
通讯作者：
Xing, Da
中科院分区：
文献类型：
--
作者：
Cao, Caijun;Nie, Liming;Xing, Da
肾结石的影像学检查对于治疗前有泌尿系结石的患者很重要。可用的成像技术包括普通X射线、超声扫描、静脉尿路造影、计算机断层扫描等。然而，尿酸结石（放射性结石）的可视化是困难的，并且通常不可能通过上述成像方法。本文提出了一种基于微波热声成像的肾结石检测方法。草酸钙结石和尿酸结石的热声图像与其X线图像进行了比较。通过热声信号的幅值可以评价草酸钙结石、尿酸结石和正常肾组织对微波吸收的差异。隐藏在猪肾中的结石在三个正交的热声图像中以良好的对比度和分辨率清晰地成像。结果表明，热声成像技术可作为肾结石诊断的一种补充手段，且成本低、效果好，具有很好的临床应用前景。
Imaging of renal calculi is important for patients who suffered a urinary calculus prior to treatment. The available imaging techniques include plain x-ray, ultrasound scan, intravenous urogram, computed tomography, etc. However, the visualization of a uric acid calculus (radiolucent calculi) is difficult and often impossible by the above imaging methods. In this paper, a new detection method based on microwave-induced thermoacoustic tomography was developed to detect the renal calculi. Thermoacoustic images of calcium oxalate and uric acid calculus were compared with their x-ray images. The microwave absorption differences among the calcium oxalate calculus, uric acid calculus and normal kidney tissue could be evaluated by the amplitude of the thermoacoustic signals. The calculi hidden in the swine kidney were clearly imaged with excellent contrast and resolution in the three orthogonal thermoacoustic images. The results indicate that thermoacoustic imaging may be developed as a complementary method for detecting renal calculi, and its low cost and effective feature shows high potential for clinical applications.