Controlling transmembrane protein concentration and orientation in supported lipid bilayers

Controlling transmembrane protein concentration and orientation in supported lipid bilayers
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DOI:
10.1039/c7cc01023k
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发表时间:
2017-04-18
影响因子:
4.9
通讯作者:
Evans, S. D.
Evans, S. D.
中科院分区:
化学2区
文献类型:
--
作者:
Bao, P.;Cartron, M. L.;Evans, S. D.

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跨膜蛋白-蛋白紫质(pR)已被纳入支持脂质双分子层(SLB)。平面内电场被用来操纵这些蛋白质的取向和浓度,在SLB内,通过电泳导致pR浓度增加25倍。
The trans-membrane protein -proteorhodopsin (pR) has been incorporated into supported lipid bilayers (SLB). In-plane electric fields have been used to manipulate the orientation and concentration of these proteins, within the SLB, through electrophoresis leading to a 25-fold increase concentration of pR.