Primary Motor and Sensory Cortex Activation during Motor Performance and Motor Imagery: A Functional Magnetic Resonance Imaging Study
Primary Motor and Sensory Cortex Activation during Motor Performance and Motor Imagery: A Functional Magnetic Resonance Imaging Study
复制标题
DOI：
10.1523/jneurosci.16-23-07688.1996
复制
发表时间：
1996-12
期刊：
影响因子：
--
通讯作者：
C. Porro;M. P. Francescato;V. Cettolo;M. Diamond;P. Baraldi;C. Zuiani;M. Bazzocchi;P. D. di Prampero-P.-D.-di-Pramp
中科院分区：
文献类型：
--
作者：
C. Porro;M. P. Francescato;V. Cettolo;M. Diamond;P. Baraldi;C. Zuiani;M. Bazzocchi;P. D. di Prampero-P.-D.-di-Pramp
采用功能性磁共振成像（fMRI）技术，对14名右利手志愿者在自主控制速度的优势手指-拇指对置动作的实际运动表现（MP）和心理表征（MI）过程中左侧中央前回和中央后回的功能激活强度和空间分布进行了研究。在MP（平均百分比增加，2.1%）和MI（0.8%）期间，在包括中央沟的前堤和冠部（推测为初级运动皮层的部位）在内的区域，平均标准化fMRI信号强度比在对照（视觉成像）任务期间获得的值显著增加。在中央前回和中央后回的前部，平均功能活动水平也在两种情况下增加（MP，1.7和1.2%; MI，0.6和0.4%，分别）。为了在MI、MP或这两种情况下定位激活的病灶，将位于中央前回或中央后回的像素信号强度的时间过程绘制为单步或双步波形，其中波形的步骤对应于不同的任务。在大多数受试者的每个区域中，MP和MI期间都发现了显著（r > 0.7）激活的像素; MI期间信号强度增加的百分比平均为MP期间增加的30%。在MP和MI期间激活的像素似乎代表在MP期间激活的整个群体的大部分。这些结果支持这一假设，即MI和MP涉及重叠的神经网络在perirolandic皮质区。
The intensity and spatial distribution of functional activation in the left precentral and postcentral gyri during actual motor performance (MP) and mental representation [motor imagery (MI)] of self-paced finger-to-thumb opposition movements of the dominant hand were investigated in fourteen right-handed volunteers by functional magnetic resonance imaging (fMRI) techniques. Significant increases in mean normalized fMRI signal intensities over values obtained during the control (visual imagery) tasks were found in a region including the anterior bank and crown of the central sulcus, the presumed site of the primary motor cortex, during both MP (mean percentage increase, 2.1%) and MI (0.8%). In the anterior portion of the precentral gyrus and the postcentral gyrus, mean functional activity levels were also increased during both conditions (MP, 1.7 and 1.2%; MI, 0.6 and 0.4%, respectively). To locate activated foci during MI, MP, or both conditions, the time course of the signal intensities of pixels lying in the precentral or postcentral gyrus was plotted against single-step or double-step waveforms, where the steps of the waveform corresponded to different tasks. Pixels significantly (r > 0.7) activated during both MP and MI were identified in each region in the majority of subjects; percentage increases in signal intensity during MI were on average 30% as great as increases during MP. The pixels activated during both MP and MI appear to represent a large fraction of the whole population activated during MP. These results support the hypothesis that MI and MP involve overlapping neural networks in perirolandic cortical areas.