Spatial distribution of the chromosomal forms of anopheles gambiae in Mali
Spatial distribution of the chromosomal forms of anopheles gambiae in Mali
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DOI：
10.1186/1475-2875-7-205
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发表时间：
2008-10-10
期刊：
影响因子：
3
通讯作者：
Toure, Yeya T.
中科院分区：
文献类型：
--
作者：
Sogoba, Nafomon;Vounatsou, Penelope;Toure, Yeya T.
背景：疟疾病媒分布图是疟疾风险分层和选择性病媒控制战略的有用工具。虽然冈比亚按蚊复合体成员的分布在非洲有很好的记录，但有一张连续的冈比亚按蚊染色体形式的空间分布图。冈比亚亚种方法：用贝叶斯地统计学方法绘制出染色体形式空间分布的连续图。冈比亚亚种(Mopti，Bamako，Savanna及其杂交种/重组体)根据它们与马里气候和环境因素的相对频率进行比较。结果：图谱清楚地显示，每种染色体形式都有利于特定定义的生态气候带。莫普提人更喜欢干旱的萨凡纳和萨赫勒北部以及尼日尔河内河三角洲的洪水/灌溉地区。萨凡纳形式有利于苏丹稀树草原地区，特别是该国南部和东南部(卡耶斯和西卡索地区)。巴马科形式对特定的环境条件有强烈的偏好，它仅限于巴马科市区周围的苏丹稀树草原地区和锡卡索地区的西部。结论：这些图谱为马里选择性媒介控制(杀虫剂耐药性管理)提供了有价值的信息，并可作为未来疟疾控制战略的决策支持工具，包括基因操纵的蚊子。
Background: Maps of the distribution of malaria vectors are useful tools for stratification of malaria risk and for selective vector control strategies. Although the distribution of members of the Anopheles gambiae complex is well documented in Africa, a continuous map of the spatial distribution of the chromosomal forms of An. gambiae s.s. is not yet available at country level to support control efforts.Methods: Bayesian geostatistical methods were used to produce continuous maps of the spatial distribution of the chromosomal forms of An. gambiae s.s. (Mopti, Bamako, Savanna and their hybrids/recombinants) based on their relative frequencies in relation to climatic and environmental factors in Mali.Results: The maps clearly show that each chromosomal form favours a particular defined eco-climatic zone. The Mopti form prefers the dryer northern Savanna and Sahel and the flooded/irrigated areas of the inner delta of the Niger River. The Savanna form favours the Sudan savanna areas, particularly the South and South-Eastern parts of the country (Kayes and Sikasso regions). The Bamako form has a strong preference for specific environmental conditions and it is confined to the Sudan savanna areas around urban Bamako and the Western part of Sikasso region. The hybrids/recombinants favour the Western part of the country (Kayes region) bordering the Republic of Guinea Conakry.Conclusion: The maps provide valuable information for selective vector control in Mali (insecticide resistance management) and may serve as a decision support tool for the basis for future malaria control strategies including genetically manipulated mosquitoes.