Gadolinium-enhanced three-dimensional MR angiography of Takayasu arteritis
Gadolinium-enhanced three-dimensional MR angiography of Takayasu arteritis
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DOI：
10.1148/rg.243035096
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发表时间：
2004-05-01
期刊：
影响因子：
5.5
通讯作者：
Cerri, GG
中科院分区：
文献类型：
--
作者：
Nastri, MV;Baptista, LPS;Cerri, GG
高须动脉炎是一种大血管炎，可能由自身免疫引起，可引起主动脉及其主要分支狭窄。高须动脉炎有六种类型；其类型取决于是否影响升主动脉、胸降主动脉、腹主动脉、颈肱动脉分支或肾动脉。冠状动脉和肺动脉有时也受累。该病的临床特征包括脉搏减少或消失、跛行、高血压和肠系膜心绞痛。传统的血管造影一直是诊断和评估高松动脉炎的标准成像工具，尽管它只显示血管的管腔。侵入性较小的横断方法，如计算机断层血管造影和最近的三维磁共振（MR）血管造影，可以有效地显示血管壁增厚，这可能是疾病的最早表现，发生在狭窄和扩张之前。尤其是MR成像能更好地鉴别软组织，并能显示其他炎症迹象，包括壁水肿和壁血管扩张。磁共振成像的其他优点是缺乏碘化造影剂或电离辐射。
Takayasu arteritis is a form of large vessel vasculitis with a possible autoimmune origin that may cause stenosis of the aorta and its major branches. Six types of Takayasu arteritis are recognized; the type depends on whether the ascending aorta, descending thoracic aorta, abdominal aorta, aortic cervicobrachial branches, or renal arteries are affected. The coronary and pulmonary arteries are also sometimes involved. Clinical features of the disease include diminished or absent pulses, claudication, hypertension, and mesenteric angina. Conventional angiography has been the standard imaging tool for diagnosis and evaluation of Takayasu arteritis, although it demonstrates only the lumen of the vessel. Less invasive cross-sectional methods such as computed tomographic angiography and, more recently, three-dimensional magnetic resonance (MR) angiography can effectively demonstrate thickening of the vessel wall, which may be the earliest manifestation of the disease, occurring before stenosis and dilatation. MR imaging in particular allows better soft-tissue differentiation and can show other signs of inflammation, including mural edema and increased mural vascularity. Other advantages of MR imaging are the lack of iodinated contrast material or ionizing radiation.