The impact of a reduction in drug supply compliance with treatment for drug on demand for and dependence
The impact of a reduction in drug supply compliance with treatment for drug on demand for and dependence
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DOI：
10.1016/j.drugalcdep.2005.01.018
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发表时间：
2005-08-01
影响因子：
4.2
通讯作者：
Hall, W
中科院分区：
文献类型：
--
作者：
Degenhardt, L;Conroy, E;Hall, W
背景资料：2001年初，澳大利亚的海洛因供应突然、急剧和持续下降，同时价格急剧上涨，街头纯度下降，即所谓的“海洛因短缺”。这些前所未有的变化是在治疗广泛提供的背景下发生的，这使得有可能第一次审查新南威尔士州海洛因供应急剧减少对海洛因依赖治疗的进入和坚持的影响。因为有证据表明一些吸毒者用毒品替代毒品。目前的文件还探讨了进入治疗其他形式的药物dependence.Methods：中断时间序列分析的人数进入阿片类药物治疗和其他治疗方式在新南威尔士州海洛因依赖和其他类型的药物dependence.Findings：海洛因短缺与进入阿片类药物治疗的年轻人的数量减少。进入海洛因戒断或“仅评估”治疗期的人数急剧减少。在海洛因供应减少后，海洛因治疗的坚持和保留情况似乎略有改善。相对较小的增长被观察到的可卡因dependence.Conclusions：在良好的治疗提供的背景下，减少海洛因供应似乎产生适度的改善中间结果。减少供应和减少需求的措施，如果都得到成功实施，可能是相辅相成的。(c)2005爱思唯尔爱尔兰有限公司保留所有权利。
Background: In early 2001, Australia experienced a sudden, dramatic and;sustained decrease in heroin availability that was accompanied by sharp increases in price and decreases in street level purity-the so-called "heroin shortage". These unprecedented changes occurred in a context of widespread treatment availability, which made it possible for the first time to examine the impact of a sharp reduction in heroin supply in New South Wales (NSW) on entry to and adherence with treatment for heroin dependence. Given the evidence of drug substitution by some users. the current paper also examines the effects of the shortage on entry to treatment for other forms of drug dependence.Methods: Interrupted time-series analysis of the number of persons entering opioid pharmacotherapy and other treatment modalities in NSW for heroin dependence and for the treatment for other types of drug dependence.Findings: The heroin shortage was associated with a reduction in the number of younger persons entering opioid pharmacotherapy. There was a dramatic decrease in the number of persons entering heroin withdrawal or "assessment only" treatment episodes. There appear to have been small improvements in adherence to and retention in heroin treatment after the reduction in heroin supply. Relatively small increases were observed in numbers being treated for cocaine dependence.Conclusions: In the context of good treatment provision, a reduction in heroin supply appeared to produce modest improvements in intermediate outcomes. Supply and demand reduction measures, when both are implemented successfully, may be complementary. (c) 2005 Elsevier Ireland Ltd. All rights reserved.