Comparison of posterior capsule opacification and glistenings with 2 hydrophobic acrylic intraocular lenses: 5-to 7-year follow-up

Comparison of posterior capsule opacification and glistenings with 2 hydrophobic acrylic intraocular lenses: 5-to 7-year follow-up
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DOI:
10.1016/j.jcrs.2012.11.032
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发表时间:
2013-05-01
影响因子:
2.8
通讯作者:
Kugelberg, Maria
Kugelberg, Maria
中科院分区:
医学2区
文献类型:
--
作者:
Chang, Anthony;Behndig, Anders;Kugelberg, Maria

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目得:目的:比较白内障手术后5 ~ 7年植入2枚疏水性丙烯酸人工晶状体(IOL)后后囊膜混浊(PCO)和闪光情况,评价其对矫正远视力(CDVA)和对比敏感度的影响。患者被随机分配至Acrysof SA 60 AT(单件式IOL组)或Sensar AR 40 e(3件式IOL组),均为锐边设计的疏水性丙烯酸IOL。术后5 - 7年,获得后照明图像,并使用计算机软件评价PCO面积和严重程度(撕囊内受影响的面积和严重程度)。测量了高对比度(100%)和低对比度(2.5%)的CDVA。记录Nd:YAG激光晶状体囊切开率。获得Scheimpflug图像,以评估glistenings,这是在裂隙灯主观分级和量化客观的数字图像分析,使用计算机software.RESULTS:该研究纳入了80例患者。两组之间的PCO无显著差异。三片式人工晶状体组的闪光明显减少(P
PURPOSE: To compare posterior capsule opacification (PCO) and glistenings 5 to 7 years after cataract surgery with implantation of 2 hydrophobic acrylic intraocular lenses (IOLs) and evaluate the effects on corrected distance visual acuity (CDVA) and contrast sensitivity.SETTING: St. Erik Eye Hospital, Stockholm, Sweden.DESIGN: Randomized clinical trial.METHODS: Cataract surgery with standard phacoemulsification was performed in 1 eye of patients. The patients were randomized to an Acrysof SA60AT (1-piece IOL group) or a Sensar AR40e (3-piece IOL group), both hydrophobic acrylic IOLs with a sharp-edged design. Five to 7 years postoperatively, retroillumination images were obtained and the PCO area and severity (area affected within the capsulorhexis and severity) were evaluated using computer software. High-contrast (100%) and low-contrast (2.5%) CDVAs were measured. The neodymium:YAG laser capsulotomy rates were recorded. Scheimpflug images were obtained to evaluate glistenings, which were graded subjectively at the slitlamp and quantified objectively by digital image analysis using computer software.RESULTS: The study enrolled 80 patients. There were no significant differences in PCO between the 2 groups. The 3-piece IOL group had significantly fewer glistenings (P