THE INHIBITORY QUOTIENT - A METHOD FOR INTERPRETING MINIMUM INHIBITORY CONCENTRATION DATA
THE INHIBITORY QUOTIENT - A METHOD FOR INTERPRETING MINIMUM INHIBITORY CONCENTRATION DATA
复制标题
DOI：
10.1001/jama.246.14.1575
复制
发表时间：
1981-01-01
影响因子：
120.7
通讯作者：
NEU, HC
中科院分区：
文献类型：
--
作者：
ELLNER, PD;NEU, HC
描述了一种报告最小抑菌浓度 (MIC) 数据的方法，该方法有助于不熟悉临床可达到的药物水平的临床医生进行解释。该系统使用抑制商，这是一个反映将达到的 MIC 倍数的数字。抑制商是针对血液、尿液、胆汁和脑脊液测定的，反映了这些体液中可达到的药物水平。抑制商的使用对于医生合理选择合适的抗菌剂非常有帮助。
A method for reporting minimum inhibitory concentration (MIC) data that facilitates interpretation by the clinician unfamilar with clinically achievable drug levels is described. This system uses the inhibitory quotient, which is a number reflecting the multiple of the MIC that would be achieved. Inhibitory quotients are determined for blood, urine, bile and CSF and reflect achievable drug levels in those body fluids. The use of inhibitory quotients can be extremely helpful to the physician in the rational selection of an appropriate antimicrobial agent.