ON THE SIGNIFICANCE OF TRANSIENTS IN DAILY RHYTHMS
ON THE SIGNIFICANCE OF TRANSIENTS IN DAILY RHYTHMS
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DOI：
10.1073/pnas.44.9.965
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发表时间：
1958-01-01
影响因子：
11.1
通讯作者：
KAUS, P
中科院分区：
文献类型：
--
作者：
PITTENDRIGH, C;BRUCE, V;KAUS, P
在试图发现的温度补偿的具体性质，自我维持的振荡的基础和控制持久的日常节奏普遍在活细胞中，作者认为一类的影响，其分析导致形成一个明确的正式模型。这些效应是在自由运行的节奏中当它们被单个相移信号扰动时产生的瞬变。耦合振荡器模型解释了瞬态的几个特点，容纳其他复杂的数据的相对作用，光和温度的控制果蝇的节奏，提供了一个独特的基础，有关每日节奏最近发现的热和光周期性，它给出了一个近似的数学表达式，点到新的实验分析线。
In an attempt to discover the concrete nature of the temperature-compensated, self-sustaining oscillation that underlies and controls the persistent daily rhythms universal in living cells, the authors consider a class of effects whose analysis leads to the formation of an explicit formal model. These effects are the transients developed in free-running rhythms when they are perturbed by single phase-shifting signals. The coupled-oscillator model explains the several peculiarities of transients, accomodates other complex data on the relative roles of light and temperature in the control of the Drosophila rhythm, provides a unique basis for relating daily rhythms to recent discoveries in thermo- and photo-periodism and it gives an approximate mathematical expression that points to new lines of experimental analysis.