A general practice-based prevalence study of epilepsy among adults with intellectual disabilities and of its association with psychiatric disorder, behaviour disturbance and carer stress
A general practice-based prevalence study of epilepsy among adults with intellectual disabilities and of its association with psychiatric disorder, behaviour disturbance and carer stress
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DOI：
10.1111/j.1365-2788.2007.01025.x
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发表时间：
2008-02-01
影响因子：
3.6
通讯作者：
Kerr, M.
中科院分区：
文献类型：
--
作者：
Matthews, T.;Weston, N.;Kerr, M.
背景虽然智力残疾（ID）人群中癫痫的发生率升高是公认的，但癫痫发作的性质及其与精神病理学和照顾者紧张的关系尚不清楚。目的是确定癫痫的患病率和特点，在社区为基础的人口与成人ID，并探讨癫痫的存在是否与更大的精神病理学或照顾strain.Methods数据收集的年龄，性别，居住地，适应性和挑战性的行为，社会能力和精神状态的318名成年人从40个一般的做法，以及家庭护理人员的不适和紧张程度。对于癫痫患者，护士通过访谈收集有关癫痫发作，调查，治疗和护理人员关注的信息。癫痫和精神疾病发病率，挑战性的行为和照顾者不适或应变之间的关联，探讨了通过比较与癫痫与对照组匹配的适应behavior.Results五十八名参与者（18%）癫痫：26%的癫痫发作免费，但34%有极差的控制癫痫发作。早期发作和发作频率与适应行为有关。照顾者的担忧与癫痫发作频率和受伤史有关。匹配的癫痫和非癫痫groups.Conclusions之间的精神病理学，照顾者不适或照顾者应变没有显着差异，这项研究支持高发病率和慢性癫痫的人ID。虽然精神病理学和照顾者应变是常见的在这个人群中，潜在的残疾相关因素似乎比癫痫本身的存在更重要。
Background Although the elevated occurrence of epilepsy in people with intellectual disabilities (ID) is well recognized, the nature of seizures and their association with psychopathology and carer strain are less clearly understood. The aims were to determine the prevalence and features of epilepsy in a community-based population of adults with ID, and to explore whether the presence of epilepsy was associated with greater psychopathology or carer strain.Methods Data were collected on the age, gender, place of residence, adaptive and challenging behaviour, social abilities and psychiatric status of 318 adults from 40 general practices, together with the degree of malaise and strain of family carets. For participants with epilepsy, a nurse collected information on seizures, investigations, treatment and carer concerns by interview. Association between epilepsy and psychiatric morbidity, challenging behaviour and caregiver malaise or strain, was explored by comparing those with epilepsy with a comparison group matched on adaptive behaviour.Results Fifty-eight participants (18%) had epilepsy: 26% were seizure free, but 34% had extremely poorly controlled seizures. Earlier onset and seizure frequency were associated with adaptive behaviour. Carer concerns were related to seizure frequency and a history of injury. There were no significant differences in psychopathology, carer malaise or caregiver strain between the matched epilepsy and non-epilepsy groups.Conclusions This study supports the high occurrence and chronicity of epilepsy among people with ID. While psychopathology and carer strain is common within this population, underlying disability-related factors appear to be more important than the presence of epilepsy per se.