Associations Between Alcohol Use, Other Psychosocial Factors, Structural Factors and Antiretroviral Therapy (ART) Adherence Among South African ART Recipients
Associations Between Alcohol Use, Other Psychosocial Factors, Structural Factors and Antiretroviral Therapy (ART) Adherence Among South African ART Recipients
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DOI：
10.1007/s10461-013-0583-0
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发表时间：
2014-03-01
影响因子：
4.4
通讯作者：
Nkosi, Sebenzile
中科院分区：
文献类型：
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作者：
Morojele, Neo K.;Kekwaletswe, Connie T.;Nkosi, Sebenzile
我们在南非茨瓦内 ART 站点的 304 名男性和女性 ART 接受者中检查了饮酒是否与抗逆转录病毒治疗 (ART) 依从性相关，而与结构和心理社会因素无关。 ART 依从性通过 CASE 依从性指数进行评估。自变量是人口、结构、心理社会和饮酒（审计评分）因素。在层次多元回归中，人口统计变量（步骤 1）解释了 ART 依从性的 4% 方差（p 为千分之一货币符号 0.01）。输入结构变量后，解释的方差增加到 16%（p 为千分之一货币符号 0.001）（步骤 2）；输入社会心理变量后为 19 %（p 为千分之一货币符号 0.001）（步骤 3）；输入审计分数（第 4 步）后，为 24%（p 为千分之一货币符号 0.001）。饮酒与 ART 依从性独立相关。
We examined whether alcohol use is associated with antiretroviral therapy (ART) adherence independently of structural and psychosocial factors among 304 male and female ART recipients in ART sites in Tshwane, South Africa. ART adherence was assessed by the CASE Adherence Index. Independent variables were demographic, structural, psycho-social, and alcohol use (AUDIT score) factors. In hierarchical multiple regression, demographic variables (Step 1) explained 4 % of variance in ART adherence (p a parts per thousand currency sign 0.01). Variance explained increased to 16 % (p a parts per thousand currency sign 0.001) after entering structural variables (Step 2); 19 % (p a parts per thousand currency sign 0.001) after entering psychosocial variables (Step 3); and 24 % (p a parts per thousand currency sign 0.001) after entering AUDIT score (Step 4). Alcohol use is independently associated with ART adherence.