SPATIAL AND TEMPORAL SIGNALING BY CALCIUM

SPATIAL AND TEMPORAL SIGNALING BY CALCIUM
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DOI:
10.1016/0955-0674(94)90146-5
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发表时间:
1994-04-01
影响因子:
7.5
通讯作者:
DUPONT, G
DUPONT, G
中科院分区:
生物学2区
文献类型:
--
作者:
BERRIDGE, MJ;DUPONT, G

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最近的研究表明,钙信号的空间和时间方面的重要性,这取决于再生性能的肌醇三磷酸和ryanodine受体,调节释放的钙从内部存储。已经发现起始位点自发地释放钙,被认为是“热点”或“火花”,并且可以触发通过钙诱导的钙释放过程传播的波。
Recent research has shown the importance of the spatial and temporal aspects of calcium signals, which depend upon regenerative properties of the inositol trisphosphate and ryanodine receptors that regulate the release of calcium from internal stores. Initiation sites have been found to spontaneously release calcium, recognized as 'hot spots' or 'sparks', and can trigger a wave that spreads through a process of calcium-induced calcium release.