Evidence of marked sexual behavior change associated with low HIV-1 seroconversion in 149 married couples with discordant HIV-1 serostatus: experience at an HIV counselling center in Zaire.
Evidence of marked sexual behavior change associated with low HIV-1 seroconversion in 149 married couples with discordant HIV-1 serostatus: experience at an HIV counselling center in Zaire.
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149 名 HIV-1 血清状态不一致的已婚夫妇中，显着性行为改变与 HIV-1 血清转化率低相关的证据：扎伊尔 HIV 咨询中心的经验。
DOI：
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发表时间：
1991
期刊：
影响因子：
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通讯作者：
W. Heyward
中科院分区：
文献类型：
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作者：
M. Kamenga;R. Ryder;Muana Jingu;Nkashama Mbuyi;L. Mbu;F. Behets;C. Brown;W. Heyward
为了确定艾滋病毒-1咨询方案对149对艾滋病毒-1血清学不一致的扎伊尔已婚夫妇的影响，在382.4人年的随访期间（每对夫妇最少随访时间为6个月）观察了艾滋病毒-1血清转化率和报告的避孕套使用率。在确定HIV-1血清状态和咨询之前，这些夫妇中只有不到5%使用过避孕套。在告知HIV-1血清状态和咨询后一个月，70.7%的夫妇报告在所有性交事件中使用避孕套。在18个月的随访中，仍在随访的140对夫妇中有77.4%报告在所有性交事件中继续使用避孕套。在通知HIV-1血清状况时，18对夫妇经历了严重的心理痛苦。除了三对后来离婚的夫妇外，受过训练的护士提供的家庭咨询解决了所有这些困难。在艾滋病毒-1血清状态不一致的扎伊尔已婚夫妇自愿参加艾滋病毒咨询中心后，在通知艾滋病毒-1血清状态后进行的密集咨询导致艾滋病毒-1血清转换率较低（每100人观察年为3.1%）。
To determine the effect of an HIV-1 counselling program on 149 married Zairian couples with discordant HIV-1 serology, the rates of HIV-1 seroconversion and reported condom utilization have been observed during 382.4 person-years of follow-up (minimum follow-up time per couple of 6 months). Before determination of HIV-1 serostatus and counselling, less than 5% of these couples had ever used a condom. One month after notification of HIV-1 serostatus and counselling, 70.7% of couples reported using condoms during all episodes of sexual intercourse. At 18 months follow-up, 77.4% of the 140 couples still being followed reported continued use of condoms during all episodes of sexual intercourse. At the time of notification of HIV-1 serostatus, 18 couples experienced acute psychological distress. Home-based counselling by trained nurses resolved these difficulties in all but three couples who subsequently divorced. Intensive counselling following notification of HIV-1 serostatus led to low rates of HIV-1 seroconversion (3.1% per 100 person-years of observation) in Zairian married couples with discordant HIV-1 serostatus who voluntarily attended an HIV counselling center.