An international expert opinion statement on the utility of PET/MR for imaging of skeletal metastases.

An international expert opinion statement on the utility of PET/MR for imaging of skeletal metastases.
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DOI:
10.1007/s00259-021-05198-2
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发表时间:
2021-05
影响因子:
9.1
通讯作者:
Catalano OA
Catalano OA
中科院分区:
医学1区
文献类型:
--
作者:
Husseini JS;Amorim BJ;Torrado-Carvajal A;Prabhu V;Groshar D;Umutlu L;Herrmann K;Cañamaque LG;Garzón JRG;Palmer WE;Heidari P;Shih TT;Sosna J;Matushita C;Cerci J;Queiroz M;Muglia VF;Nogueira-Barbosa MH;Borra RJH;Kwee TC;Glaudemans AWJM;Evangelista L;Salvatore M;Cuocolo A;Soricelli A;Herold C;Laghi A;Mayerhoefer M;Mahmood U;Catana C;Daldrup-Link HE;Rosen B;Catalano OA

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综合PET/MR是一种结合了其组成模式优势的成像技术,特别适合于骨骼转移性疾病的评估。MR可以提供高软组织对比度和多参数解剖成像,已成为评估肌肉骨骼恶性肿瘤的首选成像方式。PET提供定量的分子和生理信息,已成为恶性肿瘤诊断和分期的重要工具。在本文中,我们将简要概述同时进行PET/MR采集的技术考虑因素及其与骨转移检测和表征的相关性。我们还将讨论PET/MR方案开发的原则,这些原则可以优化骨骼转移病变的检测,重点是18F-FDG和非18F-FDG放射性药物的技术。最后,我们将回顾目前的证据,并为怀疑患有骨骼转移性疾病的患者使用PET/MR提供建议。
Integrated PET/MR is an imaging technique that combines the strengths of its constituent modalities and is uniquely suited for evaluation of skeletal metastatic disease. MR can contribute high soft tissue contrast and multiparametric anatomic imaging and has become the imaging modality of choice for assessment of musculoskeletal malignancies. PET provides quantitative molecular and physiologic information and has become a critical tool in the diagnosis and staging of malignancies. In this article, we will provide a brief overview of technical considerations for simultaneous PET/MR acquisition and their relevance to the detection and characterization of osseous metastases. We will also discuss principles for PET/MR protocol development that can optimize detection of skeletal metastatic lesions with a focus on technique for both 18F-FDG and non 18F-FDG radiopharmaceuticals. Lastly, we will review current evidence and provide recommendations for the use of PET/MR in patients for whom there is suspicion for skeletal metastatic disease.
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