Influence of Post-disaster Evacuation on Incidence of Metabolic Syndrome.

Influence of Post-disaster Evacuation on Incidence of Metabolic Syndrome.
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DOI:
10.5551/jat.35824
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发表时间:
2017-03-01
影响因子:
4.4
通讯作者:
Fukushima Health Management Survey Group
Fukushima Health Management Survey Group
中科院分区:
医学2区
文献类型:
--
作者:
Hashimoto S;Nagai M;Fukuma S;Ohira T;Hosoya M;Yasumura S;Satoh H;Suzuki H;Sakai A;Ohtsuru A;Kawasaki Y;Takahashi A;Ozasa K;Kobashi G;Kamiya K;Yamashita S;Fukuhara SI;Ohto H;Abe M;Fukushima Health Management Survey Group

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目的:东日本大地震发生后,福岛第一核电站附近超过16万居民因核事故被迫疏散。这些撤离者的健康问题已成为主要问题。我们研究了福岛居民疏散与代谢综合征(METS)发病率之间的关系。方法:我们在福岛灾难发生时没有METS的40-74岁居民中进行了一项队列研究。在灾前符合纳入标准的20,269名居民中,截至2013年3月底,有8,547名居民(男性3,697人,女性4,850人;随访比例:42.2%)在灾后仍然可以接受随访检查。主要结果是METS的发生率,由日本委员会的指南定义,使用灾难前后的综合健康检查数据。我们根据疏散状态对参与者进行了分组,并比较了各组之间的结果。使用逻辑回归模型,我们估计了METS发生率的比值比,调整了潜在的混杂因素,年龄,性别,腰围,运动习惯和饮酒量。结果:疏散人员METS的发生率(男性19.2%,女性6.6%)高于非疏散人员(男性11.0%,女性4.6%)。灾难发生后,疏散人员的体重指数、腰围、甘油三酯和空腹血糖高于非疏散人员。我们发现疏散和METS发生率之间存在显著相关性(调整后的比值比为1.72,95%置信区间为1.46-2.02)。结论:这是第一项研究表明,灾难后的疏散与METS的发病率增加有关。
Aim: After the Great East Japan Earthquake, over 160,000 residents near the Fukushima Daiichi Nuclear Power Plant were forced to evacuate due to a nuclear accident. Health problems in these evacuees have since become major issues. We examined the association between evacuation and incidence of metabolic syndrome (METS) among residents in Fukushima. Methods: We conducted a cohort study among residents aged 40–74 years without METS at the time of the disaster in Fukushima. Among 20,269 residents who met the inclusion criteria before the disaster, 8,547 residents (3,697 men and 4,850 women; follow-up proportion: 42.2%) remained available for follow-up examinations after the disaster by the end of March 2013. The main outcome was incidence of METS, defined by guidelines from the Japanese committee, using data from the Comprehensive Health Check before and after the disaster. We divided participants by evacuation status and compared outcomes between groups. Using a logistic regression model, we estimated the odds ratio for incidence of METS, adjusting for potential confounders, age, gender, waist circumference, exercise habit, and alcohol consumption. Results: Incidence of METS was higher in evacuees (men 19.2%, women 6.6%) than in non-evacuees (men 11.0%, women 4.6%). Evacuees had higher body mass index, waist circumference, triglycerides, and fasting plasma glucose after the disaster than non-evacuees. We found a significant association between evacuation and incidence of METS (adjusted odds ratio 1.72, 95% confidence interval; 1.46–2.02). Conclusion: This is the first study to demonstrate that evacuation after a disaster is associated with increased incidence of METS.