The roles of exosomal immune checkpoint proteins in tumors.
The roles of exosomal immune checkpoint proteins in tumors.
复制标题
外泌体免疫检查点蛋白在肿瘤中的作用
DOI:
10.1186/s40779-021-00350-3
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发表时间:
2021-11-08
影响因子:
21.1
通讯作者:
Peng HL
中科院分区:
文献类型:
--
作者:
Xing C;Li H;Li RJ;Yin L;Zhang HF;Huang ZN;Cheng Z;Li J;Wang ZH;Peng HL
Targeting immune checkpoints has achieved great therapeutic effects in the treatment of early-stage tumors. However, most patients develop adaptive resistance to this therapy. The latest evidence demonstrates that tumor-derived exosomes may play a key role in systemic immune suppression and tumor progression. In this article, we highlight the role of exosomal immune checkpoint proteins in tumor immunity, with an emphasis on programmed death ligand 1 (PD-L1) and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), as well as emerging evidence on roles of T cell immunoglobulin-3 (TIM-3), arginase 1 (ARG1), and estrogen receptor binding fragment-associated antigen 9 (EBAG9) expressed by exosomes.
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影响因子:
3.3
作者:
Hamanishi J;Mandai M;Matsumura N;Abiko K;Baba T;Konishi I
通讯作者:
Konishi I
DOI:
10.18632/aging.103692
发表时间:
2020-09-23
期刊:
Aging
影响因子:
--
作者:
Chen Y;Li J;Ma B;Li N;Wang S;Sun Z;Xue C;Han Q;Wei J;Zhao RC
通讯作者:
Zhao RC
影响因子:
17.1
作者:
Gao, Ling;Wang, Lu;Zhang, Jianyi
通讯作者:
Zhang, Jianyi
影响因子:
8.7
作者:
Freeman GJ;Casasnovas JM;Umetsu DT;DeKruyff RH
通讯作者:
DeKruyff RH
影响因子:
24.8
作者:
Haderk, Franziska;Schulz, Ralph;Seiffert, Martina
通讯作者:
Seiffert, Martina