Geographic Region, Racial/Ethnic Disparities, and Late-Life Depression: Results From a Large US Cohort of Older Adults.
Geographic Region, Racial/Ethnic Disparities, and Late-Life Depression: Results From a Large US Cohort of Older Adults.
复制标题
地理区域，种族/种族差异和晚期抑郁症：来自美国大批老年人的大量抑郁症。
DOI：
10.1016/j.jagp.2021.11.010
复制
发表时间：
2022-06
期刊：
影响因子：
--
通讯作者：
Okereke OI
中科院分区：
文献类型：
--
作者：
Vyas CM;Reynolds CF 3rd;Donneyong M;Mischoulon D;Chang G;Cook NR;Manson JE;Okereke OI
确定地理区域与晚年抑郁症 (LLD) 严重程度、项目级症状负担和治疗之间的关联；评估之前在总体样本中观察到的 LLD 中的种族/民族差异是否因地区而异。我们纳入了 25,502 名 VITAL（维生素 D 和 Omega-3 试验）参与者，并针对抑郁症状进行了患者健康问卷 8；参与者还报告了抑郁症的药物治疗和/或咨询护理。进行了多变量回归分析。尽管与东北部相比，中西部地区的 LLD 严重程度和项目级症状负担总体较低，但与该地区的非西班牙裔白人相比，少数族裔（尤其是黑人和西班牙裔成年人）的 LLD 严重程度和项目级负担较高。项目级症状（例如快感缺乏、悲伤、精神运动变化）的种族/民族差异因地区而异。不同地区的抑郁症护理没有显着差异；此外，在护理方面的种族差异并未观察到地区差异：例如，在临床医生诊断为抑郁症的患者中，黑人与非西班牙裔白人相比，在所有地区的治疗几率均低于 50% 以上。 LLD 因地理区域而异。此外，LLD 严重程度和项目级症状负担方面的种族/民族差异程度因地区而异，但抑郁症护理则不然。
To determine associations between geographic region and late-life depression (LLD) severity, item-level symptom burden, and treatment; to evaluate whether racial/ethnic disparities in LLD, previously observed in the overall sample, vary by region. We included 25,502 VITAL (Vitamin D and Omega-3 Trial) participants and administered the Patient Health Questionnaire-8 for depressive symptoms; participants also reported medication and/or counseling care for depression. Multivariable regression analyses were performed. Despite overall lower LLD severity and item-level symptom burden in the Midwest vs. Northeast, higher LLD severity and item-level burden were observed among minorities, especially Black and Hispanic adults, compared to non-Hispanic whites in this region. Racial/ethnic disparities in item-level symptoms (e.g., anhedonia, sadness, psychomotor changes) varied by region. There were no significant differences in depression care by region; furthermore, regional variation was not observed in racial disparities in care: e.g., among those with clinician/physician-diagnosed depression, Blacks vs. non-Hispanic whites had >50% lower odds of treatment in all regions. LLD varied by geographic region. Furthermore, magnitudes of racial/ethnic disparities in LLD severity and item-level symptom burden, but not depression care, differed by region.
登录
查看更多内容
影响因子：
12.7
作者：
Jackson JS;Knight KM;Rafferty JA
通讯作者：
Rafferty JA
影响因子：
7.2
作者：
Chang, Shun-Chiao;Wang, Wei;Okereke, Olivia I.
通讯作者：
Okereke, Olivia I.
DOI：
10.1111/j.2517-6161.1995.tb02031.x
发表时间：
1995-01-01
影响因子：
5.8
作者：
BENJAMINI, Y;HOCHBERG, Y
通讯作者：
HOCHBERG, Y
影响因子：
4.2
作者：
Leung, Cindy W.;Epel, Elissa S.;Laraia, Barbara A.
通讯作者：
Laraia, Barbara A.
影响因子：
7.2
作者：
Barry, Lisa C.;Thorpe, Roland J., Jr.;Simonsick, Eleanor M.
通讯作者：
Simonsick, Eleanor M.