Preeclampsia and associated factors among pregnant women attending antenatal care in Dessie referral hospital, Northeast Ethiopia: a hospital-based study
Preeclampsia and associated factors among pregnant women attending antenatal care in Dessie referral hospital, Northeast Ethiopia: a hospital-based study
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DOI：
10.1186/s12884-015-0502-7
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发表时间：
2015-03-29
影响因子：
3.1
通讯作者：
Ayele, Tadesse Awoke
中科院分区：
文献类型：
--
作者：
Tessema, Gizachew Assefa;Tekeste, Abebe;Ayele, Tadesse Awoke
背景：先兆子痫是埃塞俄比亚孕产妇死亡的主要原因之一。它一直在增加，并与多种因素有关，使预防这种疾病成为一项持续的挑战。然而，在埃塞俄比亚进行的研究很少。本研究的目的是评估的患病率和相关因素与先兆子痫孕妇产前保健Dessie转诊医院，东北Ethiopia.Methods：一个基于医院的横断面研究进行了Dessie转诊医院之间的2013年8月至9月。所有在Dessie转诊医院进行产前访视的孕妇均纳入本研究。共有490名孕妇参加了这项研究。资料收集采用预先测试的结构式问卷，并以面对面访谈的方式进行。将数据输入EPI info 3.5.3版统计软件，并导出到SPSS 20版统计软件包中进行进一步分析。使用描述性统计来探索与相关变量相关的数据。采用二元Logistic回归分析。计算比值比与95%可信区间（CI），以确定与先兆子痫。结果：先兆子痫的患病率在Dessie转诊医院的孕妇被发现是8.4%。有高血压家族史的女性[校正比值比（AOR）=7.19（95%CI 3.24-15.2）]、慢性高血压[AOR = 4.3（95% CI 1.33-13.9）]，年龄≥ 35岁[AOR = 4.5（95% CI 1.56-12.8）]，糖尿病家族史[AOR = 2.4（95% CI 1.09-5.6）]和未婚[AOR = 3.03（95% CI 1.12 ~ 8.2）]与子痫前期的发病有关。高血压家族史、高龄、糖尿病家族史是子痫前期的危险因素。鼓励孕妇在怀孕期间有健康寻求行为将提供一个机会，以尽早诊断先兆子痫。
Background: Preeclampsia is one of the leading causes of maternal mortality in Ethiopia. It has been increasing and linked to multiple factors, making prevention of the disease a continuous challenge. Yet few studies have been conducted in Ethiopia. This study aimed to assess the prevalence and factors associated with preeclampsia among pregnant women attending antenatal care in Dessie referral hospital, Northeast Ethiopia.Methods: A hospital-based cross-sectional study was conducted in Dessie referral hospital between August and September 2013. All pregnant women who had antenatal visit at Dessie referral hospital were included for the study. A total of 490 pregnant women were enrolled in the study. Pretested and structured questionnaire via face-to-face interview technique was used for data collection. The data were entered in to EPI info version 3.5.3 statistical software and exported to SPSS version 20 statistical package for further analysis. Descriptive statistics were used to explore the data in relation to relevant variables. Binary logistic regression analysis was employed. Odds ratio with 95% confidence intervals (CI) was computed to identify factors associated with Preeclampsia.Results: The prevalence of preeclampsia among pregnant women in Dessie referral hospital was found to be 8.4%. Women having family history of hypertension [Adjusted Odds Ratio (AOR) =7.19 (95% CI 3.24-15.2)], chronic hypertension [AOR = 4.3 ( 95% CI 1.33-13.9)], age >= 35 years [AOR = 4.5 (95% CI 1.56-12.8)], family history of diabetes mellitus [AOR = 2.4 (95% CI 1.09-5.6)] and being unmarried [AOR = 3.03 (95% CI 1.12 - 8.2)] were found to be associated with preeclampsia.Conclusions: The prevalence of preeclampsia in this hospital was lower that other studies. Having personal or family history of hypertension, older age, and family history of diabetic mellitus were factors associated with preeclampsia. Encouraging pregnant women to have health seeking behavior during pregnancy would provide a chance to diagnose preeclampsia as early as possible.