Screening for Sleep-Disordered Breathing and Excessive Daytime Sleepiness in Adolescent Girls with Polycystic Ovarian Syndrome
Screening for Sleep-Disordered Breathing and Excessive Daytime Sleepiness in Adolescent Girls with Polycystic Ovarian Syndrome
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DOI：
10.1016/j.jpeds.2011.04.027
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发表时间：
2011-10-01
影响因子：
5.1
通讯作者：
Arens, Raanan
中科院分区：
文献类型：
--
作者：
Nandalike, Kiran;Strauss, Temima;Arens, Raanan
目的 确定患有多囊卵巢综合征 (PCOS) 的少女中睡眠呼吸障碍 (SDB) 和白天过度嗜睡 (EDS) 的患病率以及临床和代谢相关性。 研究设计 对 PCOS 参与者以及年龄、性别、种族和体重指数 (BMI) z 评分匹配的对照组进行标准化问卷调查。审查医疗记录中的人体测量和代谢数据。 结果 我们研究了 103 名 PCOS 参与者（16.9 +/- 1.5 岁）和 90 名对照者（16.8 +/- 1.7 岁）。与对照组相比，患有 PCOS 的女孩的 SDB（45.6% vs 27.8%；P = .01）和 EDS（54.4% vs 35.6%；P < .01）患病率较高。在 PCOS 中，SDB 患者的 BMI z 评分较高（2.1 +/- 0.5 vs 1.7 +/- 0.6；P < .01），稳态模型评估指数较高（5.1 +/- 2.3 vs 4.1 +/- 3.5；P
Objective To determine the prevalence and clinical and metabolic correlates of sleep-disordered breathing (SDB) and excessive daytime sleepiness (EDS) in adolescent girls with polycystic ovarian syndrome (PCOS).Study design Standardized questionnaires were administered to participants with PCOS and age-, sex-, ethnicity-, and body mass index (BMI) z score-matched controls. Medical records were reviewed for anthropometric and metabolic data.Results We studied 103 participants with PCOS (16.9 +/- 1.5 years) and 90 controls (16.8 +/- 1.7 years). Compared with controls, girls with PCOS had a higher prevalence of SDB (45.6% vs 27.8%; P = .01) and EDS (54.4% vs 35.6%; P < .01). Within PCOS, those with SDB had higher BMI z score (2.1 +/- 0.5 vs 1.7 +/- 0.6; P < .01), higher homeostatic model assessment index (5.1 +/- 2.3 vs 4.1 +/- 3.5; P