Seasonal variation in a clinical referral pediatric cohort at risk for obstructive sleep apnea
Seasonal variation in a clinical referral pediatric cohort at risk for obstructive sleep apnea
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DOI：
10.1016/j.ijporl.2012.11.016
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发表时间：
2013-02-01
影响因子：
1.5
通讯作者：
Gozal, David
中科院分区：
文献类型：
--
作者：
Nakayama, Meiho;Koike, Shigefumi;Gozal, David
目的：探讨儿童阻塞性睡眠呼吸暂停(OSA)严重程度在多导睡眠图检查中的季节性变化。方法：研究人群包括连续接受夜间鼾症评估的儿童、父母亲眼目睹的睡眠呼吸暂停、睡眠呼吸困难或睡眠噪音。共有554名儿童被确定为合格儿童，并接受了整夜多导睡眠监测(PSG)。结果：青年组AHI以8月最低(9.5+/-1.7/hrTST)，老年组以12月份最低(8.7+/-2.3/hrTST)。6岁组AHI最高为1月份(24.8 7.5/hrTST)，6岁组最高为3月(32.7+/-6.9/hrTST)。结论：有临床症状的OSA儿童存在季节性变化，且随年龄的增加而不同，全球范围内夏季AHI有改善的趋势，尤其是年龄较小的儿童。未来应该进行研究，以确定PSG评估月份的“校正系数”，以便在评估有症状的习惯性打鼾症儿童时能够做出准确的决定。(C)2012爱思唯尔爱尔兰有限公司。保留所有权利。
Objective: The present study was carried to examine the hypothesis that the severity of obstructive sleep apnea (OSA) in a clinical referral population of children would manifest seasonal variability in their polysomnographic findings.Methods: The study population comprised consecutive children referred for evaluation of habitual nighttime snoring, parentally witnessed apnea during sleep, and difficult or noisy breathing during sleep. A total of 554 children were identified as eligible and underwent full-night polysomnography (PSG). Monthly fluctuation patterns in PSG measures were assessed in 2 age groups (= 6 years old).Results: In the younger group, the lowest AHI was found in the month of August (9.5 +/- 1.7/hrTST) while December emerged as the month with the lowest AHI for the older group (8.7 +/- 2.3/hrTST). The highest AHI was in January (24.8 7.5/hrTST) in the group >6 years old, and in March (32.7 +/- 6.9/hrTST) in the younger group.Conclusion: Seasonal changes are present in children with clinically symptomatic OSA and differ among younger and older children, with global trends toward improved AHI during summer, especially in younger children. Future studies should be conducted to define a "correction factor" for the month of PSG assessment that will enable accurate decision making when evaluating symptomatic children with habitual snoring. (C) 2012 Elsevier Ireland Ltd. All rights reserved.