A novel multi-set differential pulse voltammetry technique for improving precision in electrochemical sensing
A novel multi-set differential pulse voltammetry technique for improving precision in electrochemical sensing
复制标题
一种新颖的多组差分脉冲伏安技术，可提高电化学传感的精度
DOI：
10.1016/j.bios.2022.114628
复制
发表时间：
2022
影响因子：
12.6
通讯作者：
Kumar, Ratnesh
中科院分区：
文献类型：
--
作者：
Kashyap, Bhuwan;Kumar, Ratnesh
多年来，由于电路和系统以及校准标准的进步，电化学传感器已经达到了高水平的灵敏度。然而，对于如何减少随机误差和提高电化学传感器的精度，人们却很少进行探索。在这项工作中，提出了一种新的电化学方法，称为多组差分脉冲伏安法（MS-DPV），旨在减少化学和生物传感器的随机误差，从而提高精度。所提出的MS-DPV提高了精度，无需重复测量。因此，节省能源使用，时间消耗，和/或所需的材料。该方法特别适用于对采样、时间和能量使用有严格限制的便携式或现场传感解决方案。为了实现该方法，采用定制的即插即用型电化学传感系统对水杨酸（SA）进行了检测。SA是一种重要的植物激素，在植物对生物胁迫的防御反应中发挥作用。此外，由于其抗炎和镇痛的特性，SA被广泛应用于制药和医疗保健行业。与传统的差分脉冲伏安法相比，使用“4集dpv”可以将SA检测的误差降低12%。一般来说，误差方差随所建议的MS-DPV单次扫描中所取读数的数量线性减小。
Over the years, electrochemical sensors have achieved high levels of sensitivity due to advancements in electrical circuits and systems, and calibration standards. However, little has been explored towards developing ways to minimize random errors and improve the precision of electrochemical sensors. In this work, a novel electrochemical method derived from differential pulse voltammetry termed multi-set differential pulse voltammetry (MS-DPV) is proposed with the goal of reducing random errors in chemical- and bio-sensors and thereby improve precision. The proposed MS-DPV improves precision without the need to replicate measurements. Therefore, saving energy use, time consumed, and/or materials required. The method is especially suited for portable or in-field sensing solutions that have strict constraints on sampling, time and energy use. To realize the proposed method, a custom designed plug-and-play-type electrochemical sensing system was employed which was then used for detecting salicylic acid (SA). SA is a key phytohormone deployed during defense responses in plants against biotic stresses. Additionally, SA is widely used in the pharmaceutical and healthcare industry due to its anti-inflammatory and analgesic properties. Using a “4-set-DPV”, an error reduction of up to 12% was observed in SA detection when compared to conventional differential pulse voltammetry. In general, the error variance reduces linearly with the number of readings taken in a single scan of the proposed MS-DPV.