REBASE--enzymes and genes for DNA restriction and modification.

REBASE--enzymes and genes for DNA restriction and modification.
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DOI:
10.1093/nar/gkl891
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发表时间:
2007-01
影响因子:
14.9
通讯作者:
Macelis D
Macelis D
中科院分区:
生物学2区
文献类型:
--
作者:
Roberts RJ;Vincze T;Posfai J;Macelis D

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REBASE 是一个综合数据库,包含有关限制性酶、DNA 甲基转移酶和限制性修饰生物过程中涉及的相关蛋白质的信息。它包含有关识别和切割位点、同裂酶、新裂酶、商业可用性、甲基化敏感性、晶体和序列数据的完整参考信息。还包括经过实验鉴定的归巢核酸内切酶。对所有新测序的基因组进行分析以确定是否存在假定的限制系统,并且这些数据包含在 REBASE 中。内容或 REBASE 可以从 web () 浏览,选定的编译可以通过 ftp () 下载。此外,可以通过电子邮件请求每月更新。
REBASE is a comprehensive database of information about restriction enzymes, DNA methyltransferases and related proteins involved in the biological process of restriction-modification. It contains fully referenced information about recognition and cleavage sites, isoschizomers, neoschizomers, commercial availability, methylation sensitivity, crystal and sequence data. Experimentally characterized homing endonucleases are also included. All newly sequenced genomes are analyzed for the presence of putative restriction systems and these data are included within the REBASE. The contents or REBASE may be browsed from the web () and selected compilations can be downloaded by ftp (). Additionally, monthly updates can be requested via email.