The influence of obesity on short- and long-term outcomes after laparoscopic surgery for colon cancer: A case-matched study of 152 patients
The influence of obesity on short- and long-term outcomes after laparoscopic surgery for colon cancer: A case-matched study of 152 patients
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DOI：
10.1016/j.surg.2014.03.023
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发表时间：
2014-09-01
期刊：
影响因子：
3.8
通讯作者：
Milsom, Jeffrey W.
中科院分区：
文献类型：
--
作者：
Makino, Tomoki;Trencheva, Koiana;Milsom, Jeffrey W.
背景。尽管肥胖和结肠疾病的患病率不断增加，但肥胖对腹腔镜结直肠手术的短期和肿瘤学结果的影响仍不清楚。研究设计。将 76 名连续接受腹腔镜结肠切除术的体重指数 (BMI) >= 30 kg/m(2) 的肥胖患者与 76 名 BMI 为 0.99 的非肥胖患者进行匹配。关于肿瘤学结果，两组之间的总生存率和无病生存率没有统计学差异（5年总生存率86 vs 89%，P = 0.72，5年疾病生存率70 vs 77%，P = 0.70）。结论。当对选定的患者进行腹腔镜结肠切除术时，对于患有结肠癌的肥胖患者来说，腹腔镜结肠切除术似乎是一种安全合理的选择，其短期和肿瘤学结果与非肥胖患者相似。
Background. Despite the increasing prevalence of obesity and colonic diseases, the impact of obesity on short-term and oncologic outcomes of laparoscopic colorectal surgery still remains unclear.Study design. Seventy-six consecutive obese patients with body mass index (BMI) >= 30 kg/m(2) who underwent laparoscopic colectomy were matched with 76 nonobese patients with BMI .99). Regarding oncologic outcomes, there was no statistical difference in overall and disease-free survival between the two groups (5-year overall survival rate 86 vs 89%, P = .72, 5-year disease survival rate 70 vs 77%, P = .70).Conclusion. Laparoscopic colonic resection, when performed for selected patients, appears to be a safe and reasonable option in obese patients with colon cancer resulting in similar short-term and oncologic outcomes as nonobese patients.