Molecular-crowding-induced clustering of DNA-wrapped carbon nanotubes for facile length fractionation.
Molecular-crowding-induced clustering of DNA-wrapped carbon nanotubes for facile length fractionation.
复制标题
分子拥挤诱导 DNA 包裹的碳纳米管聚集，以实现轻松的长度分级。
作者：
C. Khripin;Nicholas Arnold;M. Zheng
新兴的应用需要明确长度的单壁碳纳米管（SWCNT）。然而，长度限定的SWCNT的使用是有限的，部分原因是缺乏容易获得的材料制备方法。在这里，我们提出了一种新的策略，单壁碳纳米管长度分馏的基础上分子拥挤诱导簇的形成。我们表明，加入聚乙二醇（PEG）作为拥挤剂到DNA包裹的单壁碳纳米管分散导致形成可逆的，非线性的，棒状的微簇，可以通过温和的离心收集。由于较短的SWCNT在较高的聚乙二醇浓度下形成簇，PEG浓度的逐渐增加导致长度分级的SWCNT。使用原子力显微镜（AFM），我们表明，可以得到的平均长度为60-500 nm和30-40%的标准偏差的馏分。基于分子拥挤的分级分离的概念应该适用于其他纳米颗粒分散体。
Emerging applications require single-wall carbon nanotubes (SWCNTs) of well-defined length. Yet the use of length-defined SWCNTs is limited, in part due to the lack of an easily accessible materials preparation method. Here, we present a new strategy for SWCNT length fractionation based on molecular crowding induced cluster formation. We show that the addition of polyethylene glycol (PEG) as a crowding agent into DNA-wrapped SWCNT dispersion leads to the formation of reversible, nematic, and rodlike microclusters, which can be collected by gentle centrifugation. Since shorter SWCNTs form clusters at higher polyethylene glycol concentration, gradual increase in PEG concentration results in length fractionated SWCNTs. Using atomic force microscopy (AFM) we show that fractions with average lengths of 60-500 nm and standard deviations of 30-40% can be obtained. The concept of molecular-crowding-based fractionation should be applicable to other nanoparticle dispersions.
影响因子：
38.3
作者：
Ju, Sang-Yong;Doll, Jonathan;Papadimitrakopoulos, Fotios
通讯作者：
Papadimitrakopoulos, Fotios
影响因子：
15
作者：
Feazell, Rodney P.;Nakayama-Ratchford, Nozomi;Lippard, Stephen J.
通讯作者：
Lippard, Stephen J.
DOI：
10.1016/s0021-9258(18)43240-1
发表时间：
1981-12
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
D. Atha;K. Ingham
通讯作者：
D. Atha;K. Ingham