Predictors of successful weight loss with relative maintenance of fat-free mass in individuals with overweight and obesity on an 8-week low-energy diet

Predictors of successful weight loss with relative maintenance of fat-free mass in individuals with overweight and obesity on an 8-week low-energy diet
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DOI:
10.1017/s0007114519001296
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发表时间:
2019-08-28
影响因子:
3.6
通讯作者:
Sjodin, Anders
Sjodin, Anders
中科院分区:
医学3区
文献类型:
--
作者:
Hansen, Thea Toft;Hjorth, Mads Fiil;Sjodin, Anders

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低能量饮食(LED)是诱导超重个体快速减肥的有效方法。然而,报告的无脂肪质量(FFM)的巨大损失后,LED触发足够的蛋白质含量的问题。此外,并非所有人都有相同程度的减肥成功。在超重和肥胖成年人中进行为期8周的LED,为男性提供5020 kJ/d,为女性提供4184 kJ/d(84/70 g蛋白质/d),我们的目的是研究蛋白质摄入量相对于初始FFM和FFM体重减轻比例之间的关系,以及与减肥成功相关的个体特征。我们评估了所有基线和LED后的结果。共有286名参与者(64名男性和222名女性)启动了LED,其中82%完成了,70%实现了显著的体重减轻(定义为>= 8%)。男性基线时1个中心点0-1个中心点6 g蛋白/d/kg FFM和女性基线时1个中心点1-2个中心点2 g蛋白/d/kg FFM范围内的蛋白质摄入量与FFM损失无关(P = 0中心点632)。基线时较高的三因素饮食问卷(TFEQ)饥饿和LED期间TFEQ去抑制和饥饿的减少与较大的体重减轻相关(所有P
A low-energy diet (LED) is an effective approach to induce a rapid weight loss in individuals with overweight. However, reported disproportionally large losses of fat-free mass (FFM) after an LED trigger the question of adequate protein content. Additionally, not all individuals have the same degree of weight loss success. After an 8-week LED providing 5020 kJ/d for men and 4184 kJ/d for women (84/70 g protein/d) among overweight and obese adults, we aimed to investigate the relationship between protein intake relative to initial FFM and proportion of weight lost as FFM as well as the individual characteristics associated with weight loss success. We assessed all outcomes baseline and after the LED. A total of 286 participants (sixty-four men and 222 women) initiated the LED of which 82 % completed and 70 % achieved a substantial weight loss (defined as >= 8 %). Protein intake in the range 1 center dot 0-1 center dot 6 g protein/d per kg FFM at baseline for men and 1 center dot 1-2 center dot 2 g protein/d per kg FFM at baseline for women was not associated with loss of FFM (P = 0 center dot 632). Higher Three-Factor Eating Questionnaire (TFEQ) hunger at baseline and reductions in TFEQ disinhibition and hunger during the LED were associated with larger weight loss (all P