Central vestibular compensation. Effect of the bilateral labyrinthectomy on neural activity in the medial vestibular nucleus.
Central vestibular compensation. Effect of the bilateral labyrinthectomy on neural activity in the medial vestibular nucleus.
复制标题
中枢前庭代偿。
DOI：
10.1001/archotol.1976.00780070049002
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发表时间：
1976
影响因子：
--
通讯作者：
B. Mccabe
中科院分区：
文献类型：
--
作者：
J. H. Ryu;B. Mccabe
试图重建的中央事件发生在前庭补偿的各个阶段后，在猫的双侧前庭切除术。双侧前庭切除猫没有表现出眼球震颤，但有不稳定的头部运动和广泛的步态。双侧前庭内侧核（MVN）的神经活动在代偿的关键阶段被抑制，但在急性和代偿期的神经活动是充分和正常的。实验结果表明，消除交叉抑制的影响，减少小脑抑制的影响，双边的前庭神经核在中枢补偿过程中，增强恢复神经活动的过程中，对侧前庭终末器官是不是一个驱动力的来源，负责再生的电活动在去传入MVN后，单侧前庭神经节切除术。
An attempt was made to reconstruct the central events that occurred in the various stages of vestibular compensation after a bilateral labyrinthectomy in the cat. Bilateral labyrinthectomized cats showed no nystagmus, but had unsteady head movements and wide gaits. Neural activity in both sides of the medial vestibular nuclei (MVN) was depressed during the critical stage of compensation; however, the neural activity was full and normal during the acute and compensated stage. The experimental results suggest that removing crossed inhibitory influence and reducing the cerebellar inhibitory influence by bilateral labyrinthectomy enhances the process of recovering neural activity in the vestibular nuclei during central compensation, and that the contralateral vestibular end organ is not a source of the driving force responsible for regeneration of electrical activity in the deafferented MVN after a unilateral labyrinthectomy.