Limitations of the oral calcium loading test in the management of the recurrent calcareous renal stone former.
Limitations of the oral calcium loading test in the management of the recurrent calcareous renal stone former.
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口服钙负荷试验在治疗复发性钙质肾结石中的局限性。
DOI：
10.1016/s0272-6386(83)80015-8
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
P. Keane
中科院分区：
文献类型：
--
作者：
J. Lein;P. Keane
采用口服钙负荷试验对22例特发性高钙尿症患者进行评估，并与20例正常对照进行比较。禁食12小时后，所有受试者采集两小时尿液样本，然后在牛奶中以半乳糖葡萄糖酸盐的形式摄取1克元素钙。在口服钙负荷后，连续两次收集两小时尿液。在禁食状态下，4例（18%）患者尿钙排泄（UCaE）高于正常，但没有iPTH或尿CAMP升高。在补钙后，22例患者中只有10例（45%）的UCaE ΔUCaE高于对照组（Δ =第三次和第一次尿液样本之间的UCaE差异）。我们得出的结论是，尽管在钙负荷后患者和对照组的UCaE平均值之间存在明显的差异，但数值的大量重叠否定了这种方法在个体患者常规管理中的临床实用性。仅根据高空腹UCaE来定义肾漏性高钙尿的意义仍不确定。
Twenty-two patients with idiopathic hypercalciuria were evaluated using an oral calcium loading test and compared with 20 normal controls. Following a 12-hour overnight fast, all subjects collected a two-hour urine sample after which they received 1 g elemental calcium as galacto-gluconate in milk. Two further two-hour urine collections were obtained consecutively following the oral calcium load. In the fasting state, 4 (18%) of the 22 patients had urinary calcium excretion (UCaE) above normal, but none had elevated iPTH or urinary CAMP values. After calcium loading, only 10 (45%) of the 22 patients had ΔUCaE greater than controls (Δ = difference in UCaE between third and first urine samples). We conclude that despite demonstrable differences between the mean values of patient and control groups with respect to the UCaE following calcium loading, the large overlap of values negates the clinical usefulness of such procedures in the routine management of individual patients. The definition of renal leak hypercalciuria based on a high fasting UCaE alone remains of uncertain significance.
复发性肾结石可以选择性治疗吗？
DOI：
10.1016/0002-9343(81)90214-x
发表时间：
1981
期刊：
The American journal of medicine
影响因子：
--
作者：
Pak,CY;Peters,P;Hurt,G;Kadesky,M;Fine,M;Reisman,D;Splann,F;Caramela,C;Freeman,A;Britton,F;Sakhaee,K;Breslau,NA
通讯作者：
Breslau,NA
口服钙负荷的钙尿反应作为肠道钙吸收量度的效用和局限性：与同位素钙吸收分数的比较。
DOI：
--
发表时间：
1981
期刊：
Investigative urology
影响因子：
--
作者：
Zerwekh,JE;Sakhaee,K;Pak,CY
通讯作者：
Pak,CY