Spontaneous recovery or persistence of postpartum endometritis and risk factors for its persistence in Holstein cows
Spontaneous recovery or persistence of postpartum endometritis and risk factors for its persistence in Holstein cows
复制标题
DOI：
10.1016/j.theriogenology.2009.08.010
复制
发表时间：
2010-01-15
期刊：
影响因子：
2.8
通讯作者：
Hayashi, A.
中科院分区：
文献类型：
--
作者：
Gautam, G.;Nakao, T.;Hayashi, A.
已有研究表明，奶牛产后子宫内膜炎有一种无需干预即可治愈的趋势。因此，本次现场研究的目的是确定产后子宫内膜炎临床自发恢复或持续的奶牛比例，并确定奶牛(Bos Taurus)持续子宫内膜炎的一些危险因素。对7个奶牛群的441头荷斯坦-弗里斯奶牛每月进行阴道镜检查和直肠触诊检查。如果奶牛在产后第15至60天(第0天=产犊当天)的首次检查中宫颈阴道分泌物中有脓液，则被认为患有“产后子宫内膜炎”；这被归类为轻度、粘液脓性或化脓性子宫内膜炎，或子宫内膜炎伴子宫内积液。此外，如果奶牛在61至150天内至少有一次子宫内膜炎，则被认为是“持续(或复发)的子宫内膜炎”。产后子宫内膜炎104例(23.6%)，其中25.3%的产妇临床子宫内膜炎持续或复发。持续或复发子宫内膜炎的奶牛受孕率(风险比[HR]=0.28；P<；0.001)慢于那些没有子宫内膜炎的奶牛，直到第150天。夏季产犊(OR=7.00；P=0.04)、产后早期并发症(OR=6.58；P=0.05)、中度(OR=4.03；P=0.08)、重度(OR=30.99；P=004)、粘液脓性(OR=9.54；P=0.02)和化脓性(OR=5.70；P=0.04)子宫内膜炎是子宫内膜炎持续或复发的危险因素。此外，在没有产后子宫内膜炎迹象的奶牛中，10.6%的奶牛在61至150天内被新诊断为子宫内膜炎。产后早期并发症(OR=2.82；P=0.03)和中度(OR=5.00；P=0.001)或重度(OR=12.63；P<；0.001)的尿道炎是新诊断的子宫内膜炎的危险因素。总而言之，大约四分之一患有产后子宫内膜炎的奶牛持续患有子宫内膜炎，直到或超过繁殖期。临床子宫内膜炎持续存在的危险因素为夏季产犊、产后早期并发症、临床相关的尿阴道和产后2个月内膜炎。(C)2010 Elsevier Inc.保留所有权利。
It has been stated that postpartum endometritis in dairy cows has a tendency to cure without intervention. The objectives of this field study, therefore, were to determine the proportions of cows with spontaneous clinical recovery or persistence of postpartum endometritis and to determine some risk factors for its persistency in dairy cows (Bos taurus). Holstein-Friesian cows (n = 441 lactations) from seven dairy herds were examined monthly by vaginoscopy and transrectal palpation. A cow was considered to have "postpartum endometritis" if it had pus in the cervico-vaginal discharge at the first postpartum examination during Days 15 to 60 (Day 0 = day of calving); this was classified as mild, mucopurulent, or purulent endometritis, or endometritis with fluid in uterus. Furthermore, a cow with evidence of endometritis at least once during Days 61 to 150 was considered to have "persistence (or recurrence) of endometritis." A total of 104 (23.6%) lactations had postpartum endometritis, of which 25.3% had persistence or recurrence of clinical endometritis. Cows with persistence or recurrence of endometritis became pregnant at a slower rate (hazard ratio [HR] = 0.28; P < 0.001) than those with no endometritis until Day 150. Calving in summer (odds ratio [OR] = 7.00; P = 0.04), early postpartum complications (OR = 6.58; P = 0.05), moderate (OR = 4.03; P = 0.08) and severe (OR = 30.99; P = 004) degrees of urovagina, and mucopurulent (OR = 9.54; P = 0.02) and purulent (OR = 5.70; P = 0.04) endometritis were risk factors for the persistence or recurrence of endometritis. Furthermore, 10.6% of cows that had not shown signs of postpartum endometritis had a new diagnosis of endometritis during Days 61 to 150. Some risk factors for the new diagnosis of endometritis beyond Day 60 were early postpartum complications (OR = 2.82; P = 0.03) and moderate (OR = 5.00; P = 0.001) or severe (OR = 12.63; P < 0.001) degrees of urovagina. In conclusion, approximately one quarter of cows with postpartum endometritis had persistence of endometritis until or beyond the breeding period. Risk factors for the persistence of clinical endometritis were summer calving, early postpartum complications, clinically relevant urovagina, and clinically relevant endometritis within 2 mo postpartum. (C) 2010 Elsevier Inc. All rights reserved.