Primary failure of eruption: Further characterization of a rare eruption disorder
Primary failure of eruption: Further characterization of a rare eruption disorder
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DOI：
10.1016/j.ajodo.2006.09.038
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发表时间：
2007-05-01
影响因子：
3
通讯作者：
Proffit, William R.
中科院分区：
文献类型：
--
作者：
Frazier-Bowers, Sylvia A.;Koehler, Karen E.;Proffit, William R.
后牙开咬有几种可能的原因，包括原发性出牙失败（PFE），影响最近端受累牙齿远端所有牙齿，机械出牙失败（MFE）（主要是强直），仅影响受累牙齿或牙齿，软组织干扰出牙（其他）。方法：对97例后路发疹失败患者的x线片及其他临床资料进行分析，进一步探讨PFE的特征，并与MFE进行区分。结果：97例患者中，38例诊断为明确的PFE；诊断为MFE的19例；32个被归类为不确定失败，因为他们太年轻，不能确定PFE和MFE之间的区别；8个被归入“其他”类别。PFE有两种亚型。在第1型中，受影响象限的所有牙齿在同一时间或几乎同一时间发生出牙失败。在第2型中，失败的时间呈梯度，因此在萌牙失败之前，可以观察到在最内侧受影响的牙齿后面有一些进一步的发育。38例PFE患者中有10例（26%）存在爆发问题家族史，对4个家族进行了系谱分析。这与常染色体显性遗传一致。结论：PFE和MFE的区别在临床上很重要，因为它决定了所有后牙，还是只有个别受影响的牙齿对正畸力没有反应。某些诊断通常需要进展x线片，以便观察远端到最近端受影响牙齿的萌牙模式。
Introduction: Posterior open bite has several possible causes, including primary failure of eruption (PFE) that affects all teeth distal to the most mesial involved tooth, mechanical failure of eruption (MFE) (primarily ankylosis) that affects only the involved tooth or teeth, and soft-tissue interferences with eruption (other). Methods: Radiographs and other clinical records for 97 cases of failure of posterior eruption submitted for consultation were analyzed to further characterize PFE and distinguish it from MFE. Results: Of the 97 cases, 38 were judged to be clear-cut PFE; 19 were diagnosed as MFE; 32 were classified as indeterminate failure because they were too young to be certain of the distinction between PFE and MFE; and 8 were placed in the "other" category. Two subtypes of PFE were observed. In type 1, eruption failure occurred at or near the same time for all teeth in an affected quadrant. In type 2, a gradient of the time of failure was present, so that some further development of the teeth posterior to the most mesial affected tooth was observed before eruption failure. A family history of eruption problems was noted in 10 of the 38 PFE subjects (26%), and a pedigree analysis was done for 4 families. This was consistent with autosomal dominant transmission. Conclusions: The distinction between PFE and MFE is clinically important because it determines whether all posterior teeth, or only individual affected teeth, will not respond to orthodontic force. Certain diagnosis often requires progress radiographs so that the pattern of eruption of teeth distal to the most mesial affected tooth can be observed.