MAMMALIAN STRESS RESPONSE INDUCTION OF THE GLUCOSE-REGULATED PROTEIN FAMILY

MAMMALIAN STRESS RESPONSE INDUCTION OF THE GLUCOSE-REGULATED PROTEIN FAMILY
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DOI:
10.1016/0955-0674(92)90042-b
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发表时间:
1992-01-01
影响因子:
7.5
通讯作者:
LEE A S
LEE A S
中科院分区:
生物学2区
文献类型:
--
作者:
LEE A S

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葡萄糖调节蛋白家族由位于内质网中的一组应激诱导蛋白组成。自1977年发现以来,我们对其结构,功能和调节的理解取得了重大进展。本文综述了近年来有关葡萄糖调节蛋白的生理作用及其在转录、转录后、翻译和翻译后水平的调节作用。
The glucose-regulated protein family consists of a set of stress-inducible proteins localized in the endoplasmic reticulum. Since their discovery in 1977, significant advances in our understanding of their structure, function and regulation have been made. Recent findings concerning the physiological roles played by the glucose-regulated proteins, and their regulations at the transcriptional, post-transcriptional, translational and post-translational levels are summarized.