PATCHINESS AND CORRELATIONS IN DNA-SEQUENCES
PATCHINESS AND CORRELATIONS IN DNA-SEQUENCES
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DOI：
10.1126/science.8430316
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发表时间：
1993-01-29
期刊：
影响因子：
56.9
通讯作者：
BRENDEL, V
中科院分区：
文献类型：
--
作者：
KARLIN, S;BRENDEL, V
基因组DNA的高度非随机特性可能会混淆通过标准随机过程（包括随机游走或分形模型）建模DNA序列变异的尝试。特别是，由不同组成的补丁组成的DNA的镶嵌特征可以充分解释DNA中明显的长程相关性。
The highly nonrandom character of genomic DNA can confound attempts at modeling DNA sequence variation by standard stochastic processes (including random walk or fractal models). In particular, the mosaic character of DNA consisting of patches of different composition can fully account for apparent long-range correlations in DNA.