Impacts of Nicotine and Flavoring on the Sensory Perception of E-Cigarette Aerosol

Impacts of Nicotine and Flavoring on the Sensory Perception of E-Cigarette Aerosol
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DOI:
10.1093/ntr/ntz058
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发表时间:
2020-05-01
影响因子:
4.7
通讯作者:
Lim, Juyun
Lim, Juyun
中科院分区:
医学2区
文献类型:
--
作者:
Pullicin, Alexa J.;Kim, Hyoshin;Lim, Juyun

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简介:旨在研究添加调味剂(樱桃)和尼古丁对电子烟气雾剂感知的相互作用,以及这如何影响电子烟调味液体(电子液体)的吸引力。方法:共有 19 名受试者(13 名男性,6 名女性)吸食了六种市售电子液体,其尼古丁含量(0、6、12 毫克/毫升)和樱桃味剂(4.7%)或 9.3% 体积/体积)。对于每种电子烟液,受试者首先使用标签快乐量表对气雾剂的总体喜欢/不喜欢进行评分,然后使用通用版本的标签量表对气雾剂的甜味、苦味、刺激性(刺激性)和樱桃味的感知强度进行评分。结果:主要发现是(1)添加尼古丁增加了感知的刺激性和苦味,并降低了电子烟气雾剂的感知甜味; (2)樱桃香精添加了特有的“樱桃味”,香精浓度从4.7%增加到9.3%往往会增加甜味、涩味和苦味的感知强度; (3)电子烟气雾剂的愉悦感随着尼古丁浓度的增加而降低,但不受风味水平的影响。结论:我们的研究结果表明,电子烟气雾剂的吸引力随着尼古丁浓度的增加而降低。相反,感知到的甜味会提高喜好度。樱桃调味剂浓度的增加似乎并未对任何测量的属性产生显着影响。
Introduction: To examine the interaction between an added flavoring (cherry) and nicotine on the perception of electronic cigarette (e-cigarette) aerosol and how this impacts the appeal of flavored liquids for e-cigarette (e-liquids).Methods: A total of 19 subjects (13 male, 6 female) vaped six commercially available e-liquids with varying contents of nicotine (0, 6, 12 mg/mL) and cherry flavor (4.7% or 9.3% vol/vol). For each e-liquid, subjects first rated overall liking/disliking of the aerosol using the Labeled Hedonic Scale, followed by perceived intensities of sweetness, bitterness, harshness (irritation), and cherry flavor of the aerosol using the general version of Labeled Magnitude Scale.Results: The main findings were that (1) added nicotine increased perceived irritation and bitterness, and decreased the perceived sweetness of the e-cigarette aerosol; (2) cherry flavoring added a characteristic "cherry flavor" and an increase in the flavoring concentration from 4.7% to 9.3% tended to increase perceived intensities of sweetness, harshness, and bitterness; and (3) hedonic ratings of the e-cigarette aerosol decreased as nicotine level increased, but were not affected by flavor level.Conclusions: Our findings indicate that the appeal of the e-cigarette aerosol decreases as nicotine concentration increases. Conversely, perceived sweetness improved liking. An increase in the concentration of cherry flavoring did not appear to impact any of the measured attributes to a significant degree.