Functional Magnetic Resonance Imaging of Mild Traumatic Brain Injury
Functional Magnetic Resonance Imaging of Mild Traumatic Brain Injury
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DOI：
10.1097/htr.0b013e3181e5477c
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发表时间：
2010-07-01
影响因子：
2.4
通讯作者：
Jantzen, Kelly J.
中科院分区：
文献类型：
--
作者：
Jantzen, Kelly J.
轻度创伤性脑损伤（MTBI）是一个严重的健康问题，一直难以研究，因为建立的解剖成像技术检测相关的神经损伤和功能障碍的相对不敏感。功能性磁共振成像（fMRI）为理解MTBI的神经和功能基础以及与行为和躯体症状的关系提供了可能。本文综述了近年来与MTBI研究相关的fMRI文献。MTBI的病理生理学和血氧水平依赖的功能磁共振成像反应的神经基础也被认为是特别关注的重要问题，使用功能磁共振成像调查MTBI。
Mild traumatic brain injury (MTBI) is a serious health problem that has been difficult to study because of the relative insensitivity of established anatomical imaging techniques for detecting the associated neural damage and dysfunction. Functional magnetic resonance imaging (fMRI) offers potential for understanding the neural and functional basis of MTBI and the relationship to behavioral and somatic symptoms. This article reviews the recent fMRI literature relevant to the study of MTBI. The pathophysiology of MTBI and the neural basis of the blood oxygen level-dependent fMRI response are also considered with particular focus on important issues for using fMRI to investigate MTBI.