Lifelike behavior of chemically oscillating mobile capsules
Lifelike behavior of chemically oscillating mobile capsules
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DOI：
10.1016/j.matt.2022.06.063
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发表时间：
2022-07
期刊：
影响因子：
18.9
通讯作者：
Oleg E. Shklyaev;A. Balazs
中科院分区：
文献类型：
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作者：
Oleg E. Shklyaev;A. Balazs
受单细胞物种自组织成多细胞生物的启发，我们使用理论和模拟来设计一个移动的活性微胶囊系统，该系统根据催化反应网络（CRN）产生化学物质。在溶液中，催化反应产生驱动周围流体流动的力。对流反过来又将胶囊运送到新的化学环境中，每次连续平移。因此，由一簇胶囊产生的化学信号严重依赖于相邻胶囊的接近度和空间构型。如果CRN中涉及的所有胶囊和化学产品都位于足够的接近度内，则系统会产生振荡行为，从而驱动胶囊动态自组装成能够集体行动的更大簇。这些模拟表明了潜在的化学机械机制，使单细胞单位，如阿米巴，组织成多细胞生命形式。
Inspired by the self-organization of unicellular species into multicellular organisms, we use theory and simulation to design a system of mobile, active microcapsules that produce chemicals according to a catalytic reaction network (CRN). In solution, the catalytic reactions generate a force that drives the flow of the surrounding fluid. The convective flow, in turn, transports the capsules to new chemical surroundings with each successive translation. Consequently, the chemical signal produced by a cluster of capsules is critically dependent on the proximity and spatial configuration of the neighboring capsules. If all of the capsules and chemical products involved in the CRN lie within sufficient proximity, then the system develops oscillatory behavior that drives the dynamic self-assembly of capsules into larger clusters that are capable of collective action. These simulations indicate potential chemo-mechanic mechanisms that enable single cellular units, such as ameba, to organize into multicellular life forms.