FREQUENCY-CHARACTERISTICS OF SYMPATHETIC-NERVE DISCHARGE IN ANESTHETIZED RATS
FREQUENCY-CHARACTERISTICS OF SYMPATHETIC-NERVE DISCHARGE IN ANESTHETIZED RATS
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DOI：
10.1152/ajpregu.1994.267.3.r830
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发表时间：
1994-09-01
影响因子：
--
通讯作者：
KENNEY, MJ
中科院分区：
文献类型：
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作者：
KENNEY, MJ
频域分析被用来表征基础交感神经放电（SND），并确定从交感神经在氯醛糖麻醉，压力感受器神经支配的大鼠同时记录的活动之间的关系。记录内脏神经、肾神经和腰神经的放电。提出了以下意见。1)在压力感受器神经支配的大鼠或压力感受器去神经的大鼠中，SND中约65-75%的总功率包含在9 Hz以下。2)相关的两个神经的活动的相干值显着不同，在该频带内的零。3)两条交感神经的放电间隔在相干频带内是频率依赖性的或恒定的。4)在急性应激期间，SND的频率成分和两条交感神经活动之间的关系可以改变。这些结果表明，负责大鼠基础SND的系统是由多个交感神经发生器或多个并联排列的滤波器组成的，它们能够产生不同的输出。这些回路的动态性质是由急性应激期间发生的变化揭示的。
Frequency-domain analyses were used to characterize basal sympathetic nerve discharge (SND) and to determine the relationships between the activity recorded simultaneously from sympathetic nerves in chloralose-anesthetized, baroreceptor-innervated rats. Discharges were recorded from the splanchnic, renal, and lumbar nerves. The following observations were made. 1) Approximately 65-75% of total power in SND was contained below 9 Hz in either baroreceptor-innervated rats or baroreceptor-denervated rats. 2) Coherence values relating the activity of two nerves were significantly different from zero within this frequency band. 3) The interval between the discharges of two sympathetic nerves was either frequency dependent or constant within the coherent frequency band. 4) The frequency components of SND and the relationships between the activity in two sympathetic nerves could be altered during periods of acute stress. These results suggest that the system responsible for basal SND in rats is composed of either multiple sympathetic generators or multiple filters arranged in parallel, which are capable of producing different outputs. The dynamic nature of these circuits was revealed by the changes that occurred during periods of acute stress.