Pilot, randomized trial of resistance exercise during radiation therapy for head and neck cancer
Pilot, randomized trial of resistance exercise during radiation therapy for head and neck cancer
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DOI：
10.1002/hed.23118
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发表时间：
2013-08-01
影响因子：
2.9
通讯作者：
Robbins, K. Thomas
中科院分区：
文献类型：
--
作者：
Rogers, Laura Q.;Anton, Philip M.;Robbins, K. Thomas
背景本研究的目的是确定在接受放射治疗的头颈癌患者中进行抗阻运动随机试验的可行性。方法将 15 名接受放射治疗的头颈癌患者随机分为抗阻运动组（使用阻力带）或对照组。在放射治疗地点（第 1-6 周）和家里（第 7-12 周）进行抗阻运动。结果没有发生与抗阻运动相关的严重不良事件。与对照组相比，抗阻运动与对照组相比，在 6 周时的感知疲劳（抗阻运动组的疲劳增加较小；7.4 vs 15.4，效应大小 [d] = -0.64）、6 周时的生活质量（-7.0 vs -14.4，d = 0.52）以及 6 周和 12 周时的椅子起身时间（秒）（-1.6 vs 0.4，d =分别为 -.63 和 -1.9 vs 0.1，d = -0.60）。结论 对于接受放射治疗的头颈癌患者，抗阻运动是安全可行的；有必要进行最终审判。 (c) 2012 年 Wiley periodicals, Inc. Head Neck，2013 年
BackgroundThe purpose of this study was to determine the feasibility of a randomized trial of resistance exercise in patients with head and neck cancer receiving radiation.MethodsFifteen patients with head and neck cancer receiving radiation were randomized to resistance exercise (using resistance bands) or control group. Resistance exercise occurred at the radiation therapy site (weeks 1-6) and home (weeks 7-12).ResultsNo serious adverse events occurred related to resistance exercise. Medium to large effect size differences favoring resistance exercise versus control group were noted for perceived fatigue at 6 weeks (smaller increase in fatigue for resistance exercise group; 7.4 vs 15.4, effect size [d] = -0.64), quality of life at 6 weeks (-7.0 vs -14.4, d = 0.52), and chair rise time (seconds) at 6 and 12 weeks (-1.6 vs 0.4, d = -.63 and -1.9 vs 0.1, d = -0.60, respectively).ConclusionsResistance exercise is safe and feasible in patients with head and neck cancer receiving radiation; a definitive trial is warranted. (c) 2012 Wiley Periodicals, Inc. Head Neck, 2013