The Sleep Heart Health Study: design, rationale, and methods.
The Sleep Heart Health Study: design, rationale, and methods.
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DOI：
10.1093/sleep/20.12.1077
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发表时间：
1997-12
期刊：
影响因子：
5.6
通讯作者：
S. Quan;B. Howard;C. Iber;C. Iber;J. Kiley;F. Nieto;G. O'Connor;D. Rapoport;S. Redline;
中科院分区：
文献类型：
--
作者：
S. Quan;B. Howard;C. Iber;C. Iber;J. Kiley;F. Nieto;G. O'Connor;D. Rapoport;S. Redline;
睡眠心脏健康研究(SHHS)是一项前瞻性队列研究，旨在调查阻塞性睡眠呼吸暂停(OSA)和其他睡眠障碍呼吸(SDB)是心血管疾病发展的危险因素。这项研究旨在招募6600名年龄在40岁及以上的成年参与者，他们将接受家庭多导睡眠图检查，以评估阻塞性睡眠呼吸暂停综合征和其他SDB的存在。SHHS的参与者是从正在进行的队列研究中招募的。因此，SHHS将OSA的评估添加到这些研究的方案中，并将使用已经收集的关于心血管疾病主要风险因素的数据以及与心血管疾病有关的随访和结果信息。这些队列的父母队列研究和招募目标如下：社区动脉粥样硬化风险研究(1750名参与者)、心血管健康研究(1350名参与者)、弗雷明翰心脏研究(1000名参与者)、强心脏研究(600名参与者)、纽约高血压队列(1000名参与者)以及图森呼吸道阻塞性疾病流行病学研究和健康与环境研究(900名参与者)。作为父母研究后续程序的一部分，参与者将定期接受心血管疾病事件的发生率和复发调查。这项研究为评估OSA和其他SDB作为包括心肌梗死和中风在内的重大心血管事件的风险因素提供了足够的统计力量。
The Sleep Heart Health Study (SHHS) is a prospective cohort study designed to investigate obstructive sleep apnea (OSA) and other sleep-disordered breathing (SDB) as risk factors for the development of cardiovascular disease. The study is designed to enroll 6,600 adult participants aged 40 years and older who will undergo a home polysomnogram to assess the presence of OSA and other SDB. Participants in SHHS have been recruited from cohort studies in progress. Therefore, SHHS adds the assessment of OSA to the protocols of these studies and will use already collected data on the principal risk factors for cardiovascular disease as well as follow-up and outcome information pertaining to cardiovascular disease. Parent cohort studies and recruitment targets for these cohorts are the following: Atherosclerosis Risk in Communities Study (1,750 participants), Cardiovascular Health Study (1,350 participants), Framingham Heart Study (1,000 participants), Strong Heart Study (600 participants), New York Hypertension Cohorts (1,000 participants), and Tucson Epidemiologic Study of Airways Obstructive Diseases and the Health and Environment Study (900 participants). As part of the parent study follow-up procedures, participants will be surveyed at periodic intervals for the incidence and recurrence of cardiovascular disease events. The study provides sufficient statistical power for assessing OSA and other SDB as risk factors for major cardiovascular events, including myocardial infarction and stroke.