On the role of the supramarginal gyrus in phonological processing and verbal working memory: Evidence from rTMS studies
On the role of the supramarginal gyrus in phonological processing and verbal working memory: Evidence from rTMS studies
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DOI：
10.1016/j.neuropsychologia.2013.10.015
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发表时间：
2014-01-01
期刊：
影响因子：
2.6
通讯作者：
Gracco, Vincent L.
中科院分区：
文献类型：
--
作者：
Deschamps, Isabelle;Baum, Shari R.;Gracco, Vincent L.
在语言和言语工作记忆任务中，边缘上回（SMG）被激活用于语音加工。使用rTMS，我们研究了SMG对语音加工的贡献是特定领域（特定于语音）还是更普遍的领域（特定于言语工作记忆）。在低频rTMS测试后，研究人员对受试者进行了相同/不同判断任务和n-back言语记忆任务的测试。结果表明，如果SMG的语音加工更具有共性，即与言语工作记忆需求相关，则rTMS对n-back任务的影响要大于相同/不同判断任务。进行了两个听觉实验。第一个实验表明，在工作记忆需求最小化（即相同/不同判断）的条件下，重复刺激对表现没有影响，尽管表现随语音复杂性的变化而变化。第二个实验表明，在口头工作记忆任务（n-back任务）中，语音复杂性也被操纵，受试者在刺激后执行任务的准确性降低，速度变慢，但语音的效果不受影响。研究结果证实，SMG参与言语工作记忆，但不参与声音差异的编码。(C) 2013 Elsevier Ltd.版权所有。
The supramarginal gyrus (SMG) is activated for phonological processing during both language and verbal working memory tasks. Using rTMS, we investigated whether the contribution of the SMG to phonological processing is domain specific (specific to phonology) or more domain general (specific to verbal working memory). A measure of phonological complexity was developed based on sonority differences and subjects were tested after low frequency rTMS on a same/different judgment task and an n-back verbal memory task. It was reasoned that if the phonological processing in the SMG is more domain general, i.e., related to verbal working memory demands, performance would be more affected by the rTMS during the n-back task than during the same/different judgment task. Two auditory experiments were conducted. The first experiment demonstrated that under conditions where working memory demands are minimized (i.e. same/different judgment), repetitive stimulation had no effect on performance although performance varied as a function of phonological complexity. The second experiment demonstrated that during a verbal working memory task (n-back task), where phonological complexity was also manipulated, subjects were less accurate and slower at performing the task after stimulation but the effect of phonology was not affected. The results confirm that the SMG is involved in verbal working memory but not in the encoding of sonority differences. (C) 2013 Elsevier Ltd. All rights reserved.