Interconnections between mRNA degradation and RDR-dependent siRNA production in mRNA turnover in plants
Interconnections between mRNA degradation and RDR-dependent siRNA production in mRNA turnover in plants
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DOI：
10.1007/s10265-017-0906-8
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发表时间：
2017-02
影响因子：
2.8
通讯作者：
Masayuki Tsuzuki;Kazuki Motomura;Naoyoshi Kumakura;A. Takeda
中科院分区：
文献类型：
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作者：
Masayuki Tsuzuki;Kazuki Motomura;Naoyoshi Kumakura;A. Takeda
mRNA种类的积累由mRNA的合成和降解之间的平衡决定。单个mRNA分子通过RNA降解途径被选择性地主动降解，包括5′-3′ mRNA降解途径、3′-5′ mRNA降解途径和RNA依赖性RNA聚合酶介导的mRNA降解途径。最近的研究表明，这些RNA降解途径在植物中的mRNA周转中相互竞争，并且植物具有从一组mRNA产生非编码小干扰RNA的隐藏层。本文综述了植物mRNA降解途径在mRNA周转中的作用，并讨论了一类新的植物内源性siRNA的潜在作用。
Accumulation of an mRNA species is determined by the balance between the synthesis and the degradation of the mRNA. Individual mRNA molecules are selectively and actively degraded through RNA degradation pathways, which include 5′-3′ mRNA degradation pathway, 3′-5′ mRNA degradation pathway, and RNA-dependent RNA polymerase-mediated mRNA degradation pathway. Recent studies have revealed that these RNA degradation pathways compete with each other in mRNA turnover in plants and that plants have a hidden layer of non-coding small-interfering RNA production from a set of mRNAs. In this review, we summarize the current information about plant mRNA degradation pathways in mRNA turnover and discuss the potential roles of a novel class of the endogenous siRNAs derived from plant mRNAs.