Improving the estimation of flow speed for laser speckle imaging with single exposure time.
Improving the estimation of flow speed for laser speckle imaging with single exposure time.
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DOI：
10.1364/ol.42.000057
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发表时间：
2017
期刊：
影响因子：
3.6
通讯作者：
Yang Wang;Dong Wen;Xiao Chen;Qin Huang;Ming Chen;Jinling Lu;Pengcheng Li
中科院分区：
文献类型：
--
作者：
Yang Wang;Dong Wen;Xiao Chen;Qin Huang;Ming Chen;Jinling Lu;Pengcheng Li
激光散斑对比度成像是一种全场成像技术，通过以高空间和时间分辨率绘制散斑对比度来测量血流。然而，来自静止组织的静态散射光严重降低了流速估计的准确性。在这封信中，我们提出了一种简单的校准方法来计算动态散射光的比例并校正单次曝光时间的静态散射的影响。模型和动物实验结果都表明，这种校准方法能够改进静态散射存在下相对血流的估计。
Laser speckle contrast imaging is a full-field imaging technique for measuring blood flow by mapping the speckle contrast with high spatial and temporal resolution. However, the statically scattered light from stationary tissues seriously degrades the accuracy of flow speed estimation. In this Letter, we present a simple calibration approach to calculate the proportions of dynamically scattered light and correct the effect of static scattering with single exposure time. Both the phantom and animal experimental results suggest that this calibration approach has the ability to improve the estimation of the relative blood flow in the presence of static scattering.