Functional aspects of the Leishmania donovani lipophosphoglycan during macrophage infection
Functional aspects of the Leishmania donovani lipophosphoglycan during macrophage infection
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DOI：
10.1016/s1286-4579(02)01624-6
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发表时间：
2002-07-01
影响因子：
5.8
通讯作者：
Turco, SJ
中科院分区：
文献类型：
--
作者：
Descoteaux, A;Turco, SJ
利什曼原虫前鞭毛体最丰富的表面糖缀合物是脂磷酸聚糖，一种糖基磷脂酰肌醇锚定聚合物的重复dislidide磷酸半乳糖（β 1，4）Manalpha 1-PO 4单位。这种复杂的分子具有有助于利什曼原虫在感染开始期间调节巨噬细胞信号传导途径的能力的特性。(C)2002年，Elsevier SAS科学与医学版。All rights reserved.
The most abundant surface glycoconjugate of the Leishmania promastigotes is lipophosphoglycan, a glycosylphosphatidyl-inositol-anchored polymer of the repeating disaccharide-phosphate Gal(beta1,4)Manalpha1-PO4 unit. This complex molecule possesses properties that contribute to the ability of Leishmania to modulate macrophage signaling pathways during the initiation of infection. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.