The first case report of kerion-type scalp mycosis caused by Aspergillus protuberus
The first case report of kerion-type scalp mycosis caused by Aspergillus protuberus
复制标题
长疣曲霉引起的脓癣型头皮真菌病首例报告
DOI：
10.1186/s12879-019-4144-7
复制
发表时间：
2019-06-10
影响因子：
3.7
通讯作者：
Chen, Dacan
中科院分区：
文献类型：
--
作者：
Jia, Jinjing;Chen, Min;Chen, Dacan
研究背景头皮真菌病是由皮肤癣菌引起的常见病，又称头皮炎。目前还没有由隆突曲霉引起的报道。我们报告一例罕见的由A.病例报告：一位五岁女童，入院前出现化脓性肿块伴疼痛八天，发烧二天。手术切开引流包块，当地医院静脉注射头孢呋辛和甲硝唑加重了皮损。通过形态学和生化特征的观察以及内转录间隔区（ITS）和β-微管蛋白（BT 2）的序列测定进行种属鉴定。口服和外用抗真菌药物治疗是有效的，没有复发，在6个月的临床following. ConclusionsEscherichgillus是一种机会致病真菌，其感染大多发生在患者的基础条件和免疫功能低下的状态。到目前为止，还没有关于脓癣型头皮感染的报道。本文报道了国内首例A.隆突的描述突出了真菌学检查的重要性，有助于识别罕见的病原真菌。任何沼泽状病变伴头皮脱发和对抗生素无反应应怀疑是真菌感染所致，应进行真菌学检查，尤其是儿童。
BackgroundScalp mycosis is often caused by dermatophytes and was so called tinea capitis. There is no published report caused by Aspergillus protuberus. We report a rare case of kerion-type scalp mycosis caused by A. protuberus.Case presentationA 5-year-old girl developed pyogenic mass with pain for 8 days and got a fever for 2 days prior to admission. Surgical incision and drainage of the mass, intravenous cefuroxime and metronidazole in the local hospital aggravated the skin lesions. Species identification was performed by observation of morphologic and biochemical characteristicsand sequencing of the internal transcribed spacer (ITS) and β-tubulin (BT2). Treatment with oral and topical antifungal agents was effective with no relapse during the six months of clinical follow-up.ConclusionsAspergillusis a opportunistic pathogenic fungus and its infection occurs mostly in patients with underlying conditions and immunocompromised statuses. So far no report of kerion-type scalp infection has been reported. The first case of kerion-type scalp mycosis caused by A. protuberus was described to highlight the importance of mycological examination that helps to recognize rare pathogenic fungi. Any boggy lesion with hair loss over the scalp and non-responsive to antibiotics should be suspected as resulting from fungal infection, and mycological examination should be performed, especially in children.