Deep Vein Thrombosis and Pulmonary Embolism: Two Complications of COVID-19 Pneumonia?
Deep Vein Thrombosis and Pulmonary Embolism: Two Complications of COVID-19 Pneumonia?
复制标题
DOI：
10.12890/2020_001646
复制
发表时间：
2020-01-01
影响因子：
--
通讯作者：
Magnacavallo, Andrea
中科院分区：
文献类型：
--
作者：
Poggiali, Erika;Bastoni, Davide;Magnacavallo, Andrea
冠状病毒病19（COVID-19）是一种全球性感染，最近被世卫组织紧急委员会宣布为全球卫生紧急情况。最常见的症状是发热和咳嗽，可发展为肺炎、急性呼吸窘迫综合征（ARDS）和/或终末器官衰竭。与ARDS和死亡相关的风险因素是年龄较大、合并症（例如，高血压、糖尿病、糖尿病）、嗜中性粒细胞和器官及凝血功能障碍。弥散性血管内凝血和凝血病可导致死亡。抗凝治疗与严重COVID-19肺炎的死亡率降低相关。在这份报告中，我们描述了两名发生静脉血栓栓塞的COVID-19肺炎患者。学习要点：COVID-19肺炎患者可发生深静脉血栓形成和肺栓塞。低分子量肝素预防并不能降低COVID-19肺炎患者发生静脉血栓栓塞（VTE）的风险。在出现临床体征和/或疑似VTE时，无论疾病分期如何，都应进行超声心动图和超声心动图检查。
Coronavirus disease 19 (COVID-19) is a worldwide infection which was recently declared a global health emergency by the WHO Emergency Committee. The most common symptoms are fever and cough, which can progress to pneumonia, acute respiratory distress syndrome (ARDS) and/or end-organ failure. Risk factors associated with ARDS and death are older age, comorbidities (e.g., hypertension, diabetes, hyperlipidaemia), neutrophilia, and organ and coagulation dysfunction. Disseminated intravascular coagulation and coagulopathy can contribute to death. Anticoagulant treatment is associated with decreased mortality in severe COVID-19 pneumonia. In this report we describe two patients with COVID-19 pneumonia who developed venous thromboembolism.LEARNING POINTS: Deep vein thrombosis and pulmonary embolism can occur in patients with COVID-19 pneumonia.Low-molecular-weight heparin prophylaxis does not decrease the risk of venous thromboembolism (VTE) in COVID-19 pneumonia.In the presence of clinical signs and/or suspicion of VTE, compression ultrasound and echocardiography should be always performed, irrespective of disease stage.