Synthesis of novel amino squaric acids via addition of dianion enolates derived from N-boc amino acid esters

Synthesis of novel amino squaric acids via addition of dianion enolates derived from N-boc amino acid esters
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DOI:
10.1016/j.tetlet.2004.11.044
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发表时间:
2005-01-10
影响因子:
1.8
通讯作者:
Ohfune, Y
Ohfune, Y
中科院分区:
化学4区
文献类型:
--
作者:
Ishida, T;Shinada, T;Ohfune, Y

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以N-叔丁氧羰基(N-Boc)氨基酸叔丁酯为原料,通过与方酸二异丙酯的加成反应,合成了一种新型的α-氨基方酸类似物。(C)2004爱思唯尔有限公司保留所有权利。
Novel alpha-amino squaric acid analogs were synthesized by initial addition reaction of a dianion enolate generated from N-Boc amino acid tert-butyl ester to squaric acid diisopropyl ester, and subsequent decarboxylation of the re sulting carboxylic acid moiety. (C) 2004 Elsevier Ltd. All rights reserved.