Can we contain the COVID-19 outbreak with the same measures as for SARS?
Can we contain the COVID-19 outbreak with the same measures as for SARS?
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DOI：
10.1016/s1473-3099(20)30129-8
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发表时间：
2020-05-01
影响因子：
56.3
通讯作者：
Lee, Vernon J.
中科院分区：
文献类型：
--
作者：
Wilder-Smith, Annelies;Chiew, Calvin J.;Lee, Vernon J.
2003年爆发的严重急性呼吸系统综合征（SARS）导致8000多例病例和800人死亡。通过症状监测、迅速隔离病人、严格执行所有接触者的隔离，以及在某些地区自上而下执行社区隔离，SARS最终得到了控制。通过阻断所有人与人之间的传播，SARS被有效根除。相比之下，截至2020年2月28日，自2019冠状病毒病（COVID-19）爆发以来的两个月内，已报告超过82000例COVID-19确诊病例，超过2800例死亡。尽管SARS和COVID-19之间有着惊人的相似之处，但病毒特征的差异将最终决定针对SARS的相同措施是否也能成功用于COVID-19。COVID-19在传染期、传播性、临床严重程度和社区传播程度方面与SARS不同。即使传统的公共卫生措施无法完全控制COVID-19的爆发，它们仍将有效降低高峰发病率和全球死亡人数。如果各国有迅速采取对策的政治意愿，向其他国家的出口不一定会导致迅速大规模的疫情爆发。
The severe acute respiratory syndrome (SARS) outbreak in 2003 resulted in more than 8000 cases and 800 deaths. SARS was eventually contained by means of syndromic surveillance, prompt isolation of patients, strict enforcement of quarantine of all contacts, and in some areas top-down enforcement of community quarantine. By interrupting all human-to-human transmission, SARS was effectively eradicated. By contrast, by Feb 28, 2020, within a matter of 2 months since the beginning of the outbreak of coronavirus disease 2019 (COVID-19), more than 82000 confirmed cases of COVID-19 have been reported with more than 2800 deaths. Although there are striking similarities between SARS and COVID-19, the differences in the virus characteristics will ultimately determine whether the same measures for SARS will also be successful for COVID-19. COVID-19 differs from SARS in terms of infectious period, transmissibility, clinical severity, and extent of community spread. Even if traditional public health measures are not able to fully contain the outbreak of COVID-19, they will still be effective in reducing peak incidence and global deaths. Exportations to other countries need not result in rapid large-scale outbreaks, if countries have the political will to rapidly implement countermeasures.