INTERACTION OF PHOTOPERIOD AND TESTOSTERONE ON DEVELOPMENT OF COPULATORY-BEHAVIOR IN CASTRATED MALE HAMSTERS
INTERACTION OF PHOTOPERIOD AND TESTOSTERONE ON DEVELOPMENT OF COPULATORY-BEHAVIOR IN CASTRATED MALE HAMSTERS
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DOI：
10.1016/0031-9384(78)90101-4
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发表时间：
1978-01-01
影响因子：
2.9
通讯作者：
TUREK, FW
中科院分区：
文献类型：
--
作者：
CAMPBELL, CS;FINKELSTEIN, JS;TUREK, FW
将阉割的成年雄性金仓鼠（Mesocricetus auratus）维持在刺激（ld14:10）或非刺激（ld6:18）光照周期10周，然后植入不同长度的空或充满睾酮的硅胶囊。分别在胶囊植入前和植入后10、20和40天对动物进行交配行为测试。在最后的试验中，雄激素处理过的LD 14:10仓鼠比同样处理过LD 6:18的仓鼠表现出更高的射精率。当血清雄激素水平维持在生理水平（约3 ng/ml，来自20 mm胶囊）时，与LD 6:18相比，LD 14:10的仓鼠进入和射精的数量显著增加。在试验期间对交配发展的检查揭示了光周期和雄激素的相互作用：ld14:10的动物在试验中表现出明显的改善，如果受到8,20或100毫米长的睾丸激素胶囊的刺激，而ld6:18的动物只有在植入100毫米胶囊的情况下才表现出在试验期间增加的交配。短日照10周后，去势雄仓鼠的交配行为对睾酮的刺激作用反应减弱。这种对雄激素敏感性的改变可能是光周期减少季节性繁殖期动物交配的一种方式。
Castrated adult male golden hamsters [Mesocricetus auratus] were maintained on either a stimulatory (LD 14:10) or a nonstimulatory (LD 6:18) light cycle for 10 wk, and then were implanted s.c. with empty or testosterone-filled Silastic capsules of various lengths. Animals were tested for copulatory behavior prior to capsule implantation and 10, 20 and 40 days after implantation. Androgen-treated LD 14:10 hamsters showed a higher incidence of ejaculation on the final trial than did similarly treated LD 6:18 animals. When serum androgen levels were maintained at physiological levels (about 3 ng/ml, from a 20 mm capsule), significantly greater numbers of LD 14:10 hamsters intromitted and ejaculated compared to LD 6:18 animals. Examination of the development of copulation over trials revealed an interaction of photoperiod and androgen: LD 14:10 animals showed significant improvement over trials if stimulated with 8, 20 or 100 mm long testosterone capsules, while LD 6:18 animals showed increased copulation over trials only if they were implanted with 100 mm capsules. Exposure to short days for 10 wk renders copulatory behavior of the castrate male hamster less responsive to the stimulatory effects of testosterone. This alteration in sensitivity to androgen may be one way in which the photoperiod acts to decrease copulation in seasonally breeding animals.