Validation of a single item to assess daytime sleepiness for the Swiss Transplant Cohort Study
Validation of a single item to assess daytime sleepiness for the Swiss Transplant Cohort Study
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DOI：
10.7182/pit2013788
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发表时间：
2013-09-01
影响因子：
0.8
通讯作者：
De Geest, Sabina
中科院分区：
文献类型：
--
作者：
Burkhalter, Hanna;Wirz-Justice, Anna;De Geest, Sabina
背景-肾移植受者日间嗜睡已成为免疫抑制药物治疗方案依从性受损的潜在预测因素。因此，有必要在临床实践和移植registrations. ESTA评估日间嗜睡的有效性，以评估在瑞士移植队列研究（STCS），使用美国教育研究协会的框架集成的单项措施日间嗜睡。方法，使用横断面设计，我们招募了926个家庭居住的肾移植受体的方便样本（中位年龄，59.69岁; 25%-75%四分位数[Q25-Q75]，50.27-59.69），63%男性;自移植以来的中位时间为9.42年（Q25-Q75，4.93-15.85）。白天嗜睡通过使用STCS中的单个项目和经验证的埃普沃思嗜睡量表的8个项目进行评估。受试者工作特征曲线分析被用来确定截止的STCS白天嗜睡项目对埃普沃思嗜睡量表score.Results-Based上的受试者工作特征曲线分析，得分大于4的STCS白天嗜睡项目，建议检测白天嗜睡。内容有效性很高，因为所有专家评论都是一致的。同时效度为中等（斯皮尔曼Q，0.531; P <0.001），抑郁和睡眠质量差的收敛效度虽然较低，但具有显著性（g，0.235; P <0.001和Q，0.318，P = 0.002）。组差异效度：肾移植受者中度，重度，极重度抑郁症状评分有3.4，4.3，和5.9倍的几率有白天嗜睡，分别与收件人相比，没有抑郁symptoms. Conclusion积累的证据提供证据的有效性STCS白天嗜睡项目作为一个简单的筛选规模白天嗜睡。(C)2013年NATCO，移植专业人员组织
Context-Daytime sleepiness in kidney transplant recipients has emerged as a potential predictor of impaired adherence to the immunosuppressive medication regimen. Thus there is a need to assess daytime sleepiness in clinical practice and transplant registries.Objective-To evaluate the validity of a single-item measure of daytime sleepiness integrated in the Swiss Transplant Cohort Study (STCS), using the American Educational Research Association framework.Methods-Using a cross-sectional design, we enrolled a convenience sample of 926 home-dwelling kidney transplant recipients (median age, 59.69 years; 25%-75% quartile [Q25-Q75], 50.27-59.69), 63% men; median time since transplant 9.42 years (Q25-Q75, 4.93-15.85). Daytime sleepiness was assessed by using a single item from the STCS and the 8 items of the validated Epworth Sleepiness Scale. Receiver operating characteristic curve analysis was used to determine the cutoff for the STCS daytime sleepiness item against the Epworth Sleepiness Scale score.Results-Based on the receiver operating characteristic curve analysis, a score greater than 4 on the STCS daytime sleepiness item is recommended to detect daytime sleepiness. Content validity was high as all expert reviews were unanimous. Concurrent validity was moderate (Spearman Q, 0.531; P < .001) and convergent validity with depression and poor sleep quality although low, was significant (g, 0.235; P < .001 and Q, 0.318, P = .002, respectively). For the group difference validity: kidney transplant recipients with moderate, severe, and extremely severe depressive symptom scores had 3.4, 4.3, and 5.9 times higher odds of having daytime sleepiness, respectively, as compared with recipients without depressive symptoms.Conclusion-The accumulated evidence provided evidence for the validity of the STCS daytime sleepiness item as a simple screening scale for daytime sleepiness. (C) 2013 NATCO, The Organization for Transplant Professionals